Evaluation of analgesic and anti-inflammatory effects of aerial parts of Breynia rhamnoides Muell.-Arg.
DOI:
https://doi.org/10.7439/ijpr.v5i8.2070Keywords:
Intrauterine demise of co-twin, hypofibrinogenemia, multifetal pregnancy, Neonatal encephalomalaciaAbstract
The plant Breynia rhamnoides Muell. Arg (family-Phyllanthaceae/Euphorbiaceae) was reported to have numerous potent constituents and the same plant was used for many traditional medicines. Phytochemical analysis of ethanolic extracts of Breynia rhamnoides revealed the presence of many active compounds such as flavonoids, glycosides, phenolic compounds, terpenoids, steroids and saponins. Present work describes the extraction and evaluation of analgesic and anti-inflammatory activities of aerial part extract of Breynia rhamnoides . Acute toxicity studies were performed as per OECD-423 guidelines. Toxicity signs and symptoms were not observed. Anti-inflammatory activity was evaluated by carrageenan-induced paw edema model and analgesic activity by Eddys hot plate method and Acetic acid induced writhing method in Wistar albino rats. The extract exhibited significant anti- inflammatory and peripheral analgesic activity.Downloads
Download data is not yet available.
Downloads
Published
2015-09-03
Issue
Section
Research Articles
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- Author must Submit Copyright form After acceptance of Article
How to Cite
1.
K. SC, P. BS. Evaluation of analgesic and anti-inflammatory effects of aerial parts of Breynia rhamnoides Muell.-Arg. Int J of Pharmc Res [Internet]. 2015 Sep. 3 [cited 2024 Oct. 18];5(8):186-90. Available from: https://ssjournals.co.in/index.php/ijpr/article/view/2070