Study of drug utilization pattern and adverse drug reactions among pregnant women attending antenatal outpatient department at tertiary care hospital
Keywords:
Drug utilization, pregnant women, WHO criteria, ComorbiditiesAbstract
Background: Antenatal care is the care provided by skilled health-care professionals to pregnant women and adolescent girls to ensure the best health conditions for both mother and baby during pregnancy. Pregnant women are usually excluded from clinical trials and results from animal studies need not apply to the human population. Prescribing drugs that are contraindicated in pregnancy is of great concern among health professionals. Hence, the current study was planned to evaluate the drug utilization pattern in pregnant women.
Materials and methods: A cross sectional, observational study was carried out in pregnant women who attended the antenatal outpatient department of at a tertiary care hospital. Patient details and medications were recorded in the Case Record Form. Prescribing indicators were evaluated as per WHO criteria.
Results: study was done in 600 participants and majority of the participants were in their third trimester. A total of 2040 medications were prescribed & the total number of drugs per prescription was 4±2 (mean ± SD). The most common co-morbidity found was anaemia (82.16%) & commonly prescribed drug was ferrous sulphate plus folic acid FDC (94.5%).92% drugs were prescribed by their generic names. C and id CL (Clindamycin+Clotrimazole pessary) was the most commonly prescribed drug (16.33%) by its brand name. 50% drugs were prescribed from the NLEM. The highest prevalence of prescribed drugs belonged to category A (46.66%). It has been observed that Tenofovir, Lamivudine and Efavirenz FDC was the most commonly associated drug with ADR.
Conclusion: This study provides an insight regarding utilization pattern of a wide variety of drug classes in pregnant women who attended the antenatal outpatient department of Obstetrics and Gynecology in a tertiary care hospital.
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