Comparative study of 0.375% bupivacaine and 0.375% ropivacaine in brachial plexus block via supraclavicular approach
DOI:
https://doi.org/10.7439/ijbr.v6i2.1601Abstract
Objectives: To compare the effect of 35 ml of 0.375% bupivacaine and 35 ml of 0.375% ropivacaine in supraclavicular brachial plexus block. Materials and Methods: In this prospective double blind study, sixty patients of ASA- I and II scheduled for upper limb orthopedic surgeries were randomly divided into Group B and Group R which received 35 ml of 0.375% bupivacaine and 0.375% ropivacaine respectively. Sensory and motor block onsetand duration and duration of analgesia were evaluated statistically using unpaired t-test and p-value 0.05 was considered significant. Results: The sensory and motor onset (mean-minutes) was 21.13 and 25.87 in group Band was 13.3 and 21.37 in group R respectively. The duration of sensory and motor block (mean- minutes) was 480.3 and 472.8 in group R, and 472.1 and460.2 in group B The duration of post-operative analgesia was 504.2 minutes in Group R and 499.6 minutes in Group B. Conclusion: Group R provided statistically significant and rapid onset of sensory and motor blockade than Group B for upper limb surgeries. There were no significant differences in duration of sensory and motor blockade, any complication or side effects. Ropivacaine may be a preferred option because of its higher therapeutic index.Downloads
References
Prithvi Raj P. Development of Regional Anaesthesia; 3rd edition; Chapter-Historical Aspects of Regional Anaesthesia, P23.
Rynd F; Neuralgia-Introduction of fluid to the nerve; Dublin Med Press 13:167, 1845.
Cousins MJ Bridenbaugh. Neural blockade in clinical anaesthesia and pain medicine. 4th Edition.: Lippincott Williams and Wilkins; 2009.
Kullenkampff D: Anaesthesia of the brachial plexus; Zantralbl Chir 38:1337-1340, 1911.
Mc Clure JH. Ropivcaine. British Journal of Anaesthesia 1996; 76:300-7.
Raikwar Surendra, Sonal Awasya, Gupta Pankaj.
Vaghadia H, Chan V, Ganapathy S, Lui A, McKenna J, Zimmer K;A multicentre trial of ropivacaine 7.5 mg x ml(-1) vs bupivacaine 5 mg x ml(-1) for supra clavicular brachial plexus anesthesia; Can J Anaesth. 1999 Oct; 46(10):946-51.
Borgeat A, Kalberer F, Jacob H, Ruetsch YA, Gerber C. Patient-controlled inter
Nishiyama T et al. Comparison of the Motor and Sensory Block by Ropivacaine and Bupivacaine in Combination with Lidocaine in Interscalene Block; Med Arh. 2012 Oct; 66(5): 315-317.
Casati A, Fanelli G, Albertin A, Deni F, Anelati D, Antonino FA, Beccaria P ; Interscalene brachial plexus anesthesia with either 0.5% ropivacaine or 0.5% bupivacaine.; Minerva Anestesiol. 2000 Jan-Feb; 66(1-2):39-44.
Hofmann-Kiefer K, Herbrich C, Seebauer A, Schwender D, Peter K.; Ropivacaine 7.5 mg/ml versus bupivacaine 5 mg/ml for interscalene brachial plexus block--
Hansen TG. Ropivacaine: A pharmacological review. Expert Rev Neurother 2004; 4:781.
Nunez Aguado D, Lopez Alvarez S, Salamanca Montana ME, Janeiro Amela M, Fernandez Fernandez R, Cobian Llamas JM. Brachial plexus block with levobupivacaine at the humeral canal: comparison of a small volume at high concentration with a large volume at low concentration. Rev Esp Anestesiol Reanim 2005; 52:529-35.
Raikwar Surendra, Sonal Awasya, Gupta Pankaj.
Tripathi D, Shah K, Shah C, Shah S, Das E et al. Supraclavicular brachial plexus block for upper limb orthopaedic surgery: a randomized, double blinded comparison between ropivacaine and bupivacaine; The International Journal of Anesthesiology, Nov 2012 (30): 4.
Hickey Rosemary, Hoffman Joan, Ramamurthy Somayaji. A comparison of Ropivacaine o.5% and Bupivacaine 0.5% for brachial plexus blolck; Anesthesiology, 1991; (74): 639-642.
Senel Ahmet Can, Ukinc Ozlem, Timurkaynak Alper; Clinical Study: Does the Addition of Tramadol and Ketamine to Ropivacaine Prolong the Axillary Brachial Plexus Block?; BioMed Research International 2014 (2014), Article ID 686287, http://dx.doi.org/10.1155/2014/686287
Klein SM, Greengrass RA, Steele SM, D'Ercole FJ, Speer KP, Gleason DH, DeLong ER, Warner DS.;A comparison of 0.5% bupivacaine, 0.5% ropivacaine, and 0.75% ropivacaine for interscalene brachial plexus block; Anesth Analg. 1998 Dec; 87(6):1316-9.
Hickey R, Rowley CL, Candido KD, Hoffman J, Ramamurthy S, Winnie AP;A comparative study of 0.25% ropivacaine and 0.25% bupivacaine for brachial plexus block; Anesth Analg. 1992 Oct; 75(4):602-6.
Da Conceicao MJ, Coelho L; Caudal anaesthesia with 0.375% ropivacaine or 0.375% bupivacaine in paediatric patients; British Journal of Anaesthesia,1998 Apr;80(4):507-8.
Brown DL, Carpenter RL, Thompson GE; Comparison of 0.5% ropivacaine and 0.5% bupivacaine for epidural anesthesia in patients undergoing lower-extremity surgery. Anesthesiology 72:633-636, 1990.
Bertini Laura, Tagariello Vincenzo, Mancini Stefania, Ciaschi Alma, Posteraro Carla Maria, Pia Di Benedetto, Martini Ornella. 0.75% and 0.5% ropivacaine for axillary brachial plexus block: A clinical comparison with 0.5% bupivacaine; American Society of Regional Anesthesia and Pain Medicine; 1999 (24)6:493-600.
Raeder J.C, Drosdahl S, Klaastad O, Kvalsvik O, Isaksen B., Stromskag K. E, Mowinckel P, Bergheim R, Selander D. Axillary brachial plexus block with ropivacaine 7.5 mg/ml: A comparative study with bupivacaine 5 mg/ml; Acta Anaesthesiologica Scandinavica 1999; 43 (8): 794
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