Phytochemical Analysis of Leaf Extract of Abutilon hirtum (Lam.) Sweet by GC-MS Method
DOI:
https://doi.org/10.7439/ijpr.v5i8.2345Abstract
Abutilon hirtum (Lam.) Sweet (Malvaceae) commonly known as Vadathuthi . It is used as one of the most important drugs in traditional system of medicine to treat various ailments. The plant is used for to its various properties as demulcent, diuretics, anti-diabetics, anthelmintic, laxative, wound healing properties, antibacterial and antifungal properties. The present study revealed the presence of phytochemicals like Diethyl Phthalate (19.171%),Benzaldehyde 4-propyl (5.219%),Methoxyacetic acid 3-tridecyl ester (5.196%),Sulfurous acid dodecyl 2-propyl ester (0.455%),Sulfurous acid, butyl dodecyl ester (0.442%) etc ., from the chloroform extracts of leaves in A. hirtum . In the present study an attempt was made to investigate the phytochemical present in the extracts in the preliminary level by using Gas Chromatography coupled with Mass Spectrometry (GC-MS). The study will provide information for the correct identification of the crude drug. This will be further considered for pharmacological activities and isolation of individual components would however, help to find new drugs.The results are reported for the first time in A. hirtum.Downloads
References
Nostro A, Germano MP, Dangelo V, Cannatelli MA. Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity. Lett. Appl. Microbiol. 2000. 30: 379-384.
Gadre AY, Uchi DA, Rege NN, Daha SA. Nuclear variations in HPTLC Fingerprint patterns of marketed oil formulations of Celastrus paniculates. Indian Journal of Pharmacology. 2001. 33:124-45.
Perumal B. Abutilon hirtum (Lam) Sweet. An Valkenburg, J.L.C.H. and Bunyapraphatsara, N. (Eds.), Plant Resources of South-East Asia: Medicinal and poisonous plants 2, Backhuys Publisher, Leiden, the Netherlands. 2001. 12(2): 30-31.
Kapoor SL, Kapoor LD. Medicinal plant wealth of the Karimnagar district of Andhra Pradesh, Bull. Med. Ethnobotanic. Res. 1980. 1: 120-144.
Pullaiah T. Medicinal plants of India, Regency publications, India. 2002.1: 9.
Chandana BK, Saxena AK, Sangeeta S, Sharma N, Gupta DK, Singh K, et al. Hepatoprotective activity of Woodfordia fruticosa flowers against carbon tetrachloride induced hepatotoxicity, J. Ethnopharmacol. 2008. 1(19): 218
Mauersberger HR. Textile fibers: their physical, microscopic and chemical properties, 6th Edition, John Wiley and Sons, New York, United States. 1954.
Avijeet J, Manish S, Lokesh D, Anurekha J, Rout SP, Gupta VB, et al. Antioxidant and hepatoprotective activity of ethanolic and aqueous extracts of Momordica dioica Roxb. Leaves, J. Ethnopharmacol. 2000. 115: 61
Srinivas Reddy K, Sanjeevakumar A, Gnananath K, Ganapathy S.Hepatoprotective potential of Abutilon hirtum Sweet leaves in carbon tetrachloride induced hepatotoxicity, Asian J. Biomed. Pharm. Sci. 2011. 1(3): 26-31.
Getahun Tadesse, Reneela P, Aman Dekebo. Isolation and characterization of natural products from Helinus mystacinus (Rhamnaceae). Journal of Chemical and Pharmaceutical Research. 2012. 4(3):1756-1762.
Sermakkani M, Thangapandian V. GC-MS Analysis of Cassia italica leaf methanol extract. Asian Journal of Pharmaceutical and Clinical Research. 2012. 5 (2), 90-94.
Ronald Hites A. Gas chromatography mass spectroscopy, Handbook of instrumental techniques for analytical chemistry. 1997. 609-611.
Vivekraj P, Vijayan A, Anandgideon V, Muthuselvam D. Phyto-chemical profiling of Abutilon hirtum (Lam.) Sweet. leaf extracts using GC-MS analysis. World Journal of Pharmaceutical Research. 2015. 4(3): 1270-1275.
Kalimuthu K, Prabakaran R. Preliminary phytochemical screening and GC-MS analysis of methanol extract of Ceropegia pusilla, International Journal of Research in Applied Natural and Social Science. 2013. 1(3): 49-58.
Anonymous. Final report on the safety assessment of di-butyl phthalate, dimethyl phthalate and diethyl phthalate. Journal of the American college of Toxicology.1985. 4(3):267-303.
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- Author must Submit Copyright form After acceptance of Article