Multi-drug Resistant Pseudomonas aeruginosa Isolated from Intensive Care Burn Unit
DOI:
https://doi.org/10.7439/ijbr.v5i4.584Abstract
Background: Pseudomonas aeruginosa is an opportunistic pathogen that develops life-threatening infections in patients with immunological system defects like burn patients. P. aeruginosa is naturally resistant as well as able to get acquired resistance to effective antibiotics which lead to problematic conditions. This study was designed to isolate P. aeruginosa from burn patients and to evaluate drug susceptibility for determination of multidrug-resistant isolates of P. aeruginosa . Materials and Methods: A prospective study was carried out on the patients visiting Victoria Hospital, Kalasipalayan, Bangalore, India from Nov 15, 2010 to June 15, 2011. The pus sample was collected using sterile cotton swab from 100 patients with burn wound infections. P. aeruginosa were identified by standard bacteriological methods. The drug susceptibility pattern using 12 antimicrobial agents (Amikacin, Ciprofloxacin, Gentamicin, Cefotaxime, Imipenem, Meropenem, Cefoperozone, Tobramycin, Piperacillin/Tazobactum, Cefepime, Ceftazidime, and Norfloxacin) were performed for all the isolates using Kirby Bauers Disc Diffusion Method. Results: P. aeruginosa were isolated from 17 clinical samples and all of these isolates were Multidrug Resistance P. aeruginosa (MDRPa). Resistance rates to various antibiotics were as follows: Amikacin (47.1%) Ciprofloxacin (35.5%) Gentamicin (47.1%) Cefotaxime (76.5%) Imipenem (88.2%) Meropenem (94.1%) Cefoperozone (94.1%) Tobramycin (100%) Piperacillin/Tazobactum (82.4%) Cefepime (64.7%) Ceftazidime (70.6%) Norfloxacin (70.6%). Conclusion: Optimization of using antimicrobial agents and control of infection is recommended to prevent the increasing population of MDRPa in the new burn centre setting in this study.Downloads
Download data is not yet available.
Downloads
Published
2014-04-22
Issue
Section
Original Research Articles
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- An author must submit Copyright form After acceptance of the article.
How to Cite
1.
Multi-drug Resistant Pseudomonas aeruginosa Isolated from Intensive Care Burn Unit. Int Jour of Biomed Res [Internet]. 2014 Apr. 22 [cited 2024 Oct. 18];5(4):271-3. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/993