Comparative prevalence of MDR S. typhi in Northern and Southern parts of Karnataka, South India

Authors

  • Rajashekar Sidramappa Yelheri
  • Channappa T. Shivannavar
  • Subhaschandra M. Gaddad

DOI:

https://doi.org/10.7439/ijbr.v5i3.573

Abstract

Typhoid fever due to infection of MDR Salmonella enterica serovar typhi resistance to Chloramphenicol, ampicillin and cotrimoxazole has posed a serious therapeutic challenge in many parts of the world, including South India. Till recently ciprofloxacin was the drug of choice for the treatment for the MDR S.typhi. However treatment failure to ciprofloxacin has been recorded with decreased susceptibility to nalidixic acid, which is the marker for ciprofloxacin resistance in S.typhi . Alternative drugs for the treatment of MDR S. typhi the cephalosporins; however, emergence of cephalosporins resistance is a matter of concern. This prompted us to study drug resistance patterns among S. typhi isolates from North Karnataka, which is endemic for typhoid fever and compared with South Karnataka which is non endemic region and formulate the appropriate drugs for the management of enteric fever.

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Author Biography

  • Rajashekar Sidramappa Yelheri
    deportment of microbiology

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Published

2014-03-29

Issue

Section

Original Research Articles

How to Cite

1.
Comparative prevalence of MDR S. typhi in Northern and Southern parts of Karnataka, South India. Int Jour of Biomed Res [Internet]. 2014 Mar. 29 [cited 2024 Oct. 18];5(3):215-7. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/976

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