Synthesis, characterization and biological evaluation of some novel substituted-(6H-thiazolo[4,5-e]indol-2-yl)-amines and substituted benzylidene-(1H-indol-4-yl)-amines

Authors

  • Raghu Vardhan Reddy Mekala Department of Chemistry, Kakatiya University, Warangal, Andhra Pradesh 506-009
  • Mahipal Reddy Yata Department of Chemistry, Kakatiya University, Warangal, Andhra Pradesh 506-009,
  • Ravi Prasad Talagadadivi Department of Chemistry, Kakatiya University, Warangal, Andhra Pradesh 506-009,

DOI:

https://doi.org/10.7439/ijbr.v5i2.531

Abstract

A series of various novel substituted-(6 H -thiazolo[4,5- e ]indol-2-yl)-amines (4a-d) and substituted benzylidene-(1 H -indol-4-yl)-amines (5a-f) have been synthesized by involving 4-nitro-1 H -indole (1) as starting compound and 4-amino-1 H -indole (2) and 1-(1 H -indol-4-yl)-3-substituted-thioureas (3a-d) as intermediates. After structural confirmation, the title compounds were screened for their antibacterial and antifungal activity.

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Published

2014-02-28

Issue

Vol. 5 No. 2 (2014): Feb

Section

Original Research Articles

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How to Cite

1.
Synthesis, characterization and biological evaluation of some novel substituted-(6H-thiazolo[4,5-e]indol-2-yl)-amines and substituted benzylidene-(1H-indol-4-yl)-amines. Int Jour of Biomed Res [Internet]. 2014 Feb. 28 [cited 2026 Mar. 9];5(2):128-31. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/952