A study on morphology of placenta and umbilical cord in Hypertensive pregnancy with and without Proteinuria
DOI:
https://doi.org/10.7439/ijbr.v4i1.793Abstract
Objectives: Pregnancy induced hypertension is a common pathological condition related to pregnancy. It may be expressed with and without proteinuria. The PIH without proteinuria is a precondition before onset of true preeclampsia. The prime objective of the study is to compare and evaluate the morphological alteration of placenta and umbilical cord in pregnancy induced hypertension with and without proteinuria. Methods: A Total sample of 80 placenta from hypertensive mothers were collected for the study, with proteinuria and without poteinuria of 40 samples each. Of the total parameters observed ,Baby weight, gestational age, APGAR scores were noted from the Patient case sheet. The placental Weight , volume, cotyledon, diameter, feto placental ratio,and thickness , and the Umbilical cord insertion site, length, coiling index, and diameter were measured and compared statistically by using t- test. Results: It was observed that, out of the total parameters, The Baby weight, The Placental volume, weight , thickness of center and margin, gestational age, feto placental ratio varies significantly between preeclampsia group (With Proteinuria) and gestational hypertensive group(Without Proteinuria).In the rest of the Parameters no material variations were observed statistically( ie: Diameter and Cotyledon of Placenta, APGAR scores and the umbilical cord dimensions cord length, diameter at 3 sites, coiling index, site of insertion) Conclusions: The study reveals that, the alteration of morphological parameters of placenta have a main role in the increased functional insufficiency and associated fetal growth retardation in the progress of hypertensive condition from gestational hypertension to preeclampsia.
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