AN IN-VITRO STUDY OF TIGECYCLINE SUSCEPTIBILITY AMONG MULTIDRUG RESISTANT BACTERIA IN A TERTIARY CARE HOSPITAL

Authors

  • Rouchelle Tellis Yenepoya Medical College, Mangalore- 575018

DOI:

https://doi.org/10.7439/ijbr.v3i4.370

Abstract

Background and objectives: Emergence and spread of antibiotic resistance among bacteria pose a challenge to clinicians due to limited therapeutic options available. Multi drug resistant (MDR) bacteria are known to cause life threatening infections in intensive care settings. Tigecycline is a newer glycycline antibiotic, considered as therapeutic option for MDR gram positive and gram negative bacteria. Aim of this study was to evaluate in-vitro susceptibility of tigecycline in MDR bacteria. Methods : We studied the in-vitro activity of tigecycline in 100 MDR bacteria isolated from blood, skin, soft tissue and surgical site infections, urine, sputum, bronchoalveolar lavage, CSF and other body fluids of patients admitted to a tertiary care hospital in South India. MDR bacteria tested for tigecycline susceptibility by disc diffusion and E-test included: Methicillin resistant S.aureus (MRSA) (35), extended spectrum β lactamase (ESBL) producing Enterobacteriaceae (36), P.aeruginosa (15) and Acinetobacter spp . (14). Results: Tigecycline was found effective against all isolates of MRSA (MIC90 0.25

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Author Biography

  • Rouchelle Tellis, Yenepoya Medical College, Mangalore- 575018
    Assistant Professor,Department of Microbiology,

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Published

2012-05-01

Issue

Vol. 3 No. 4 (2012): Apr

Section

Original Research Articles

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How to Cite

1.
AN IN-VITRO STUDY OF TIGECYCLINE SUSCEPTIBILITY AMONG MULTIDRUG RESISTANT BACTERIA IN A TERTIARY CARE HOSPITAL. Int Jour of Biomed Res [Internet]. 2012 May 1 [cited 2026 Mar. 11];3(4):192-5. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/731