CLINICAL STUDY OF RADIO ACTIVE IODINE UPTAKE IN DIFFERENT GOITRE CASES IN CO-RELLATION WITH NORMAL INDIVIDUALS
DOI:
https://doi.org/10.7439/ijbr.v3i3.331Keywords:
Goitre, RAIU, RIAK-5/5aAbstract
Aim: to measure the radioactive iodine uptake in different variants of goiter
Materials & Methods: subjects with normal levels of T 3,T4 & TSH and no goiter (control group) and examination group which is divided in to three sub groups eu-thyroid goiter, hypo-thyroid goiter and hyper-thyroid goitre cases. Each group is having 10 subjects. All the subjects are females aged 35 yrs±5 and no one is receiving any drugs since 6 weeks just before the beginning of the study.
Results and Observations: At 2 hrs: in hypo-thyroid cases RAIU is elevated, in hyper-thyroid subjects RAIU uptake is increased and in eu-thyroid subjects the uptake is decreased. At 24 hrs: in hypo-thyroid cases RAIU is decreased, in hyper-thyroid subjects RAIU uptake is increased and in eu-thyroid subjects the uptake is decreased in comparison with the control group.
Conclusion: Radioactive iodine uptake is increased at 2 hrs and decreased at 24 hrs and 48 hrs in hypo-thyroid subjects, P value is significant at 24 and 48 hrs only.
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