CLINICAL STUDY OF RADIO ACTIVE IODINE UPTAKE IN DIFFERENT GOITRE CASES IN CO-RELLATION WITH NORMAL INDIVIDUALS

Authors

  • Yogananda Reddy Indla RIMS ONGOLE
  • Shakeela Dasari Andhra Medical College, Vishakapatnam
  • Ragam Ravi Sunder RIMS ONGOLE
  • Purru Ravi Kumar RIMS ONGOLE
  • Rajani Santha Kumari MIMS Ghanpur Medchal Mandal Hyderabad, A.P

DOI:

https://doi.org/10.7439/ijbr.v3i3.331

Keywords:

Goitre, RAIU, RIAK-5/5a

Abstract

Aim: to measure the radioactive iodine uptake in different variants of goiter

Materials & Methods: subjects with normal levels of T 3,T4 & TSH and no goiter (control group) and examination group which is divided in to three sub groups eu-thyroid goiter, hypo-thyroid goiter and hyper-thyroid goitre cases. Each group is having 10 subjects. All the subjects are females aged 35 yrs±5 and no one is receiving any drugs since 6 weeks just before the beginning of the study.

Results and Observations: At 2 hrs: in hypo-thyroid cases RAIU is elevated, in hyper-thyroid subjects RAIU uptake is increased and in eu-thyroid subjects the uptake is decreased. At 24 hrs: in hypo-thyroid cases RAIU is decreased, in hyper-thyroid subjects RAIU uptake is increased and in eu-thyroid subjects the uptake is decreased in comparison with the control group.

Conclusion: Radioactive iodine uptake is increased at 2 hrs and decreased at 24 hrs and 48 hrs in hypo-thyroid subjects, P value is significant at 24 and 48 hrs only.

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Author Biographies

  • Yogananda Reddy Indla, RIMS ONGOLE
    Department of Physiology
  • Shakeela Dasari, Andhra Medical College, Vishakapatnam
    Department of Physiology
  • Ragam Ravi Sunder, RIMS ONGOLE
    Department of Physiology
  • Purru Ravi Kumar, RIMS ONGOLE
    Department of Physiology
  • Rajani Santha Kumari, MIMS Ghanpur Medchal Mandal Hyderabad, A.P
    Department of Physiology

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Published

2012-04-01

Issue

Section

Original Research Articles

How to Cite

1.
CLINICAL STUDY OF RADIO ACTIVE IODINE UPTAKE IN DIFFERENT GOITRE CASES IN CO-RELLATION WITH NORMAL INDIVIDUALS. Int Jour of Biomed Res [Internet]. 2012 Apr. 1 [cited 2026 Mar. 8];3(3):151-6. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/724