Evaluation of oxidative stress and cardiometabolic profile in hypothyroidism children

Oxidative stress in hypothyroidism children

Authors

  • Usha Dudeja Associate Professor, Department of Biochemistry, Super Speciality Pediatric Hospital and Post Graduate Teaching Hospital, Noida, U.P.
  • Rahul Saxena Associate Professor, Biochemistry Department, Sharda University, Greater Noida

DOI:

https://doi.org/10.7439/ijbr.v10i10.5263

Keywords:

Dyslipidemia, lipid peroxidation, hypothyroidism, cardiovascular disease

Abstract

Background: Despite massive efforts, oxidative stress along with abnormality in cardiometabolic profile is a serious concern in children and adolescent. However, in this context, limited studies have been documented in hypothyroidism (HT) young patients.

Aim: The objective of present study was to determine the oxidative stress and metabolic profile (glycemic and lipid profile) in young hypothyroidism patients and to determine their role in disease complexity.

Material & Method: Fasting blood glucose, serum insulin, thyroid and lipid profile (serum total cholesterol, triglycerides, HDL, LDL and VLDL levels) along with marker of lipid peroxidation (malondialdehyde; MDA) were estimated by using standard methods in 25 patients of HT as Group II, and compared it with 25 age matched young healthy controls (Group I). The values were expressed as Mean

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Published

2019-11-03

Issue

Vol. 10 No. 10 (2019): Oct

Section

Original Research Articles

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How to Cite

1.
Evaluation of oxidative stress and cardiometabolic profile in hypothyroidism children: Oxidative stress in hypothyroidism children. Int Jour of Biomed Res [Internet]. 2019 Nov. 3 [cited 2025 Mar. 12];10(10):e5263. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/5263