Contributory roles of lipids, adiposity and the underlying effect of antioxidant levels in the aetiology of breast cancer in Nigerian women

Authors

  • Kayode S Adedapo Department of Chemical Pathology, University of Ibadan and University College Hospital, Ibadan
  • Lilian F Ogungbemi Department of Chemical Pathology, University of Ibadan and University College Hospital, Ibadan
  • Temitope Oyewole Olusanya Department of Chemical Pathology, University of Ibadan and University College Hospital, Ibadan

DOI:

https://doi.org/10.7439/ijbr.v10i4.5136

Keywords:

Lipids, oxidative stress, breast cancer

Abstract

The susceptibility of lipids to oxidation has been suggested as a mechanism that can contribute to the burden of breast cancer. To further elucidate this relationship, this study sought to know if a direct relationship exists between lipid levels, adiposity and oxidative stress in individuals with breast cancer. A total of 100 (100) female participants (50 patients and 50 age-matched apparently healthy individuals as control) were recruited. Blood samples were analyzed for Total cholesterol, Triglyceride (TG), High density lipoprotein cholesterol (HDL), Total antioxidant status (TAS), Calcium and Albumin spectrophotometrically. There was a significant decrease (p<0.05) in HDL cholesterol of the patients compared to the control group while the total antioxidant status was found to be higher in the control group than in the case (1.08

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Author Biography

  • Temitope Oyewole Olusanya, Department of Chemical Pathology, University of Ibadan and University College Hospital, Ibadan

    Postgraduate student with the department of chemical Pathology, University of Ibadan/University College Hospital Nigeria.

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Published

2019-04-30

Issue

Vol. 10 No. 4 (2019): Apr

Section

Original Research Articles

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How to Cite

1.
Contributory roles of lipids, adiposity and the underlying effect of antioxidant levels in the aetiology of breast cancer in Nigerian women. Int Jour of Biomed Res [Internet]. 2019 Apr. 30 [cited 2025 Mar. 12];10(4):e5136. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/5136