Prevalence of subclinical Rickets Among Sickle cell anemic children at the Jos University Teaching Hospital, North-Central Nigeria.
DOI:
https://doi.org/10.7439/ijbr.v10i2.5001Keywords:
Subclinical Rickets, Sickle cell AnemiaAbstract
Introduction: Bone diseases are a common co-morbidity in sickle cell anemic (SCA) children. In our environment skeletal abnormalities are well documented but there is limited documentation on metabolic bone disorders, such as rickets, despite the heighten risk in these children. Furthermore, differentiation between the clinical features of rickets and that of SCA is challenging because of an overlap of clinical features.
Aim: To determine the prevalence of subclinical rickets (SR) in the study population.
Methods: This was a cross-sectional study amongst SCA children aged 2-18 years. All 113 subjects randomly sampled had their clinical and demographic data taken. Blood sample were also taken for calcium, phosphate and alkaline phosphatase assay. Data was computed using EPI info version 7.0 statistical software. SR was compared with socio-economic variables using the chi square test or fisher exact score at 95% confidence interval.
Results: Subclinical rickets was present in 21.2% of the studied population and was significantly association with age (P = 0.01). However SR was not association gender, social economic status, religion and place of residence.
Conclusion: SR is a medical burden among children presenting with sickle cell anemia in JUTH. In order to maximize health potentials, children with SCA should be screened for SR in our environment.
Downloads
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- An author must submit Copyright form After acceptance of the article.