Cytomorphological Evaluation of Breast Lesions in Rural Tertiary Care Centre
DOI:
https://doi.org/10.7439/ijbr.v9i9.4924Abstract
Background and Objectives: Breast cancer is the leading cause of morbidity and mortality worldwide. Benign as well as malignant breast lesions are quite common in Indian population. It is the second most common cancer site after cancer cervix. The present research was undertaken to study the cytomorphological patterns of various breast lesions diagnosed on Fine Needle Aspiration cytology. Method: This study was carried out on 211 patients who presented with palpable lumps in breast in the Department of Pathology, Shri Vasantrao Naik Government Medical College, Yavatmal, Maharashtra, from Jan 2017 to Jan 2018 and were subjected to an FNAC procedure after obtaining a detailed history and conducting a general physical and local examination. Cytological diagnosis was made and histopathological correlation was made, wherever available. Result: Total 211 cases were studied, the incidence of breast lesions was maximum in the age ranged from 21 to 30 years [121 (57.34%)]. There were 98.57% female patients. Of the total cases, 177 were in the benign category and 34 belonged to the malignant category. Among 211 cases, 107 cases (50.71%) were available for histopathological examination. Most commonly encountered benign breast lesion was fibroadenoma (87/177; 49.15%). Most commonly encountered malignant breast lesion was invasiveductal carcinoma(IDC) [32/34; 94.11%]. Conclusion: From present study it is evident that benign breast lesions are common than malignant lesions. The simplicity, rapidity, lack of morbidity, and cost effectiveness of FNAC makes it the most valuable tool in the evaluation of both neoplastic and non-neoplastic breast lesions.Downloads
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References
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Meena SP, Hemrajani DK, Joshi N. A comparative and evaluative study of cytological and histological grading system profile in malignant neoplasm of breast — An important prognostic factor. Indian J Pathol Microbiol 2006; 49:199-202.
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Chalya PL, Manyama M, Rambau PF, Kapesa A, Ngallaba SE, Masalu N et al. Clinicopathological pattern of benign breast diseases among female patients at a tertiary health institution in Tanzania. Tanzania J Health Res. 2016; 18(1).
Pandey A, Mishra K.B, Gaur B.S, Singh R. The diagnostic utility of FNAC in palpable lesions of breast at a tertiary care centre. Int J Med Res Rev 2017; 5(03): 338-345.
Shanmugasamy K et al. Cyto-histological correlation of breast lump- as a part of internal quality control. Indian Journal of Pathology and Oncology 2016; 3(2): 328-335.
Nguansangiam S, Jesdapatarakul S, Tangjitgamol S. Accu¬racy of fine needle aspiration cytology from breast masses in Thailand. Asian Pac J Cancer Prev 2009; 10(4):623–6.
Sankaye SB, Dongre SD. Cytological study of palpable breast lumps presenting in an Indian rural setup. Indian J Med Paediatr Oncol 2014; 35:159-64.
Domínguez F, Riera JR, Tojo S, Junco P. Fine needle aspiration of breast masses. An analysis of 1,398 patients in a community hospital. Acta Cytol 1997; 41:341-7.
Ferlay JBF, Pisani P, Parkin DM. GLOBOCAN 2000: Cancer Incidence, Mortality and Prevalence Worldwide, version 1.0. 2001. Geneva: WHO.
Dixon J M, Mansel RE.ABC of breast diseases. Symptoms assessment and guidelines for referral. BMJ. 1994; 309(6956):722-26.
Koorapati R, Bookya K. A study on clinical and pathological correlation of benign breast lesions. Int Surg J 2017; 4:2700-5.
Santen RJ, Mansel R. Benign breast disorders. N Engl J Med. 2005; 353:275-85.
Douglas J, Merchant MD. Benign Breast Diseases. Obst Gynaecol Clinics of North America. 2002; 29(1): 1-2.
Haagensen CD. The basis forthe histologic grading of carcinoma of the breast. Amer. Cancer 19 (1933), 235. Diseases of the breast. WB Saunders Co., Philadelphia and London: 1956.
Goehring C, Morabia A .Epidemiology of Benign Breast Disease, with Special Attention to Histologic Types. Epidemiol Rev.1997; 19(2):310-22.
Singh P, Chaudhry M, Nauhria S, Rao D. Cytomorphological patterns of breast lesions diagnosed on fine-needle aspiration cytology in a tertiary care hospital. Int J Med Sci Public Health 2015; 4:674-679.
Meena SP, Hemrajani DK, Joshi N. A comparative and evaluative study of cytological and histological grading system profile in malignant neoplasm of breast — An important prognostic factor. Indian J Pathol Microbiol 2006; 49:199-202.
Hadded FS. Re: Risk Factors for perineal seeding of prostate cancer after needle biopsy. J Urol. 1990; 143:587–588.
Ilaiah M, Purnaiah M, Pasha M. Evaluation of Benign Breast Diseases with Clinico, Pathological and Radiological Correlation. Indian J Appl Res. 2015; 5(11).
Mallikarjuna, Maralihalli SS. Clinico-pathological study of benign breast disease. Indian J Basic Appl Med Res. 2015:4(2): 39-46.
Bhargava GS, Gupta A, Grover A, Ded KS. Benign breast disorders: rural Punjab population study compared with urban population studies. Int Surg J. 2015; 2(4):629-33.
Kumar AD, Jayashankar E, Shailaja P, Ramamurti T. Expression of Estrogen, Progesterone and HER2/ neu Receptors in Breast Carcinoma- Study in a Tertiary Care Hospital. J Evolut Med Dent Sci. 2015; 4(58):10170-7.
Dandapat MC, Panda BK. Fine needle aspiration as a primary adjunct in the diagnosis of palpable breast lumps. J Indian MA. 1986; 84(1):3.
Mulka A, Kotasthane VD et al. Correlation of Histopathological Study of Breast Lesions with Cytology and Mammography as a Measure of Internal Quality and Diagnostic Accuracy. Annals of Pathology and Laboratory Medicine 2017; 4(4): A-398-A-402.
Rasheed A, Sharma S, Rasool M, Bashir S, Hafiz A, Bashir N. A three year study of breast lesions in women aged 15- 70 years in a tertiary care hospital. Sch J App Med Sci. 2014; 2(IB):166-68.
Chandanwale SS, Gupta K, Dharwadkar AA, Pal S, Buch AC, Mishra N. Pattern of palpable breast lesions on fine needle aspiration: A retrospective analysis of 902 cases. Journal of Mid-Life Health. 2014; 5(4):186-191.
Vijayabharathi, A. Bhagyalakshmi, J. Rajendra Prasad, S. Satish Kumar. Prospective Study of CYTO Histopathological Correlation of Breast Lesions. Journal of Evidence based Medicine and Healthcare. June 15, 2015; 2 (24):3577-3586.
Chalya PL, Manyama M, Rambau PF, Kapesa A, Ngallaba SE, Masalu N et al. Clinicopathological pattern of benign breast diseases among female patients at a tertiary health institution in Tanzania. Tanzania J Health Res. 2016; 18(1).
Pandey A, Mishra K.B, Gaur B.S, Singh R. The diagnostic utility of FNAC in palpable lesions of breast at a tertiary care centre. Int J Med Res Rev 2017; 5(03): 338-345.
Shanmugasamy K et al. Cyto-histological correlation of breast lump- as a part of internal quality control. Indian Journal of Pathology and Oncology 2016; 3(2): 328-335.
Nguansangiam S, Jesdapatarakul S, Tangjitgamol S. Accu¬racy of fine needle aspiration cytology from breast masses in Thailand. Asian Pac J Cancer Prev 2009; 10(4):623–6.
Sankaye SB, Dongre SD. Cytological study of palpable breast lumps presenting in an Indian rural setup. Indian J Med Paediatr Oncol 2014; 35:159-64.
Domínguez F, Riera JR, Tojo S, Junco P. Fine needle aspiration of breast masses. An analysis of 1,398 patients in a community hospital. Acta Cytol 1997; 41:341-7.
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2018-09-28
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Cytomorphological Evaluation of Breast Lesions in Rural Tertiary Care Centre. Int Jour of Biomed Res [Internet]. 2018 Sep. 28 [cited 2025 Mar. 12];9(9):338-41. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/4924