Prediction of hypertensive disorders in pregnancy by estimation of maternal serum beta HCG levels in the mid-trimester (13-20 weeks) of pregnancy
DOI:
https://doi.org/10.7439/ijbr.v9i10.4903Keywords:
Forensic Science, Forensic anthropology, Stature, foot outline (3D footprint), Iban ethnicsAbstract
Background : Hypertensive disorders of pregnancy (HDP) are one of the dreaded complications of pregnancy. Although improvements in obstetric and neonatal care have led to a reduction in morbidity and mortality from hypertensive disorders, our ability to predict the condition has not improved significantly. Aims and Objectives : To study the correlation of the second trimester (13-20 weeks) maternal serum beta HCG levels and the development of hypertensive disorders during pregnancy. Methods : This was a prospective study conducted in a Bihar medical college in the Department of Obstetrics and Gynaecology, over a period of 2 years. Total 100 pregnant patients, during the second trimester (13-20 weeks) were recruited from reproductive and child health OPD and serum beta HCG estimation were done in all the patients. Patients were followed till delivery and six weeks postpartum for the development of hypertensive disorders and pregnancy outcomes. Results : Total 100 patients were recruited and only 90 patients completed the study. Results were analyzed statistically. Patients were divided into two groups, group 1 was normotensive patients 86.66% (78/90) and group 2 was patients who develop hypertensive disorders 13.33% (12/90), all were pre-eclampsia. Out of 40 cases with serum beta HCG levels >35,000 mIU/ml, 25% (10/40) cases developed hypertensive disorders and out of 50 cases with serum beta HCG levels 35,000 mIU/ml, only 4.0% (2/50) cases developed hypertensive disorders. On comparison of the two groups, the p-value came out to be 0.003, which is statistically significant. Conclusion : The present study concluded that the mid-trimester (13-20 weeks) maternal serum beta HCG estimation is a good predictor for the development of hypertensive disorders during pregnancy.Downloads
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