Spectrum of colonic lesions with cytohistological correlation
DOI:
https://doi.org/10.7439/ijbr.v9i8.4855Keywords:
Energy expenditure, Body mass, Speed, Walking, RunningAbstract
Background: Colon is the site of broad array of diseases and is frequently affected by infectious, inflammatory and neoplastic disorders. It is the most common site of gastrointestinal neoplasia in western population. Many benign lesions if not detected in time can progress to malignancy over time. Cancer diagnosis very often results in an enormous change in patient psychological well being but at the same time, early diagnosis and prompt treatment plays a very important role in survival of the patient. Flexible colonoscope is well established in procuring histologic and cytologic material for microscopic evaluation. Colonoscopic direct vision brush cytology has several advantages that are not equally possessed by tissue biopsies. Objectives were to study cytomorphological features of colonic lesions, to correlate them with histopathology and evaluate sensitivity and specificity ofcytological evaluation. Methods : In present study, 200 cases ofcolonic lesions were evaluated cytologically and cytohistopathological correlation was done where possible. Result : In present study sensitivity of 96.6 % and specificity of 100 % was observed for cytological evaluation. Conclusion: Brush cytology is a reliable, safe, inexpensive and rapid method of diagnosing gastrointestinal lesions.Downloads
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References
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2. Mishra V, Mishra SP et al. Microscopic colitis in patients presenting with diarrhea. Indian Journal of Pathology and Microbiology 2010; 53: 15-18.
3. McAllister TA. Diagnosis of Amoebic colitis on routine biopsy from Rectum and Sigmoid colon. British Medical Journal 1962; 362-364.
4. Milville DM, Pirichman et al. Brush cytology of colon and rectum in ulcerative colitis: an aid to cancer diagnosis. J Clin Pathol 1988; 41: 1180-1186.
5. Muto T, Konishi F, Swada T, Adachi M, Morioka Y. Colonoscopic polypectomy as a tool for management of colonic polyps and detection of new lesions. Ann Acad Med Singapore,1987; 16 (3) : 427 31. Bazaz Malik G, Lal N. Malignant Tumors of the Digestive Tract. A twenty five years study. Indian Journal of Pathology and Microbiology 1989; 32: 179-185.
6. Dinshaw KA, Shastri SS, Patil SS. Cancer control program in India: Changes for the New Millenium. Health Administrator 2005; 17, Number 1: 10-13.
7. Geisinger KR. Alimentary Tract. In Bibbo M, editor. Comprehensive Cytopathology. 2nd edition. Philadelphia; W.B. Saunders Company. 1997; 413-444.
8. Rangaswamy R, Sahadedev R, Suguna B, Preethan K, Ranjeeta S. Clinico-colonoscopic and histomorphological spectrum of colonic diseases in an a academic tertiary care centre. 2014; 31: 1-9.
9. Tatomirovic Z, Skuletic V, Tufegdzic I, Tomic L, Dzambas J, Tarabar D. The value of brush cytology and biopsy for the diagnosis of colorectal cancer. Original article VSP. UDC: 616-348/351-076.
10. Pandey MS, Pandey A, Dombale VD. Histomorphological Profile of Colonscopic Biopsies-A Two Year study in a Tertiary care Hospital in South India. IJSR 2016: 5.611 Volume 5, Issue: 2.
11. Sayeed MA, Islam R, Siraji D, Hoque MG, Mohsen AQM. Colonoscopy: A Study of Findings in 332 patients. JCMCTA 2007; 18(2): 28-31.
12. Sulegaon R, Shete S and Kulkarni D. Histological Spectrum of Large Intestinal Lesions with clinicopathological correlation. J Clin Diagn Res. 2015; 9(11): EC30-EC34
13. Brouwer R, MacDonal A, Mathews R, Gunn J, Monson JR, Hartley JE. Brush cytology for diagnosis of colorectal cancer. Dis Colon Rectum, 2009; 52(4): 598-601.
14. Geramizadeh Bita, Hooshmand Farhang, Kumar Petricala V. Brush cytology of colorectal malignancies. Acta Cytol 2003; 47: 431-434.
15. Sharma P, Mishra V, Singh PA, Misra SP, Gupta SC. Acorrelative study of histology and imprint cytology in the diagnosis of gastrointestinal malignancies. IJPM. 1997; 40(2): 139-46.
16. Sharma P, Mishra V, Singh PA, Misra SP, Gupta SC. Acorrelative study of histology and imprint cytology in the diagnosis of gastrointestinal malignancies. IJPM. 1997; 40(2): 139-46.
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2018-08-31
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Spectrum of colonic lesions with cytohistological correlation. Int Jour of Biomed Res [Internet]. 2018 Aug. 31 [cited 2025 Mar. 12];9(8):280-6. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/4855