Thyroid Dysfunction in Patients with Metabolic Syndrome and Its Relationship with Components of Metabolic Syndrome

Abstract

Introduction - Iodine deficiency disorder (IDD) and Metabolic syndrome (Mets) has been associated with risk factors of cardiovascular disease (CVD). IDD is risk factor for CVD mediated by effects of thyroid hormone on lipid metabolism and blood pressure hence the components of Mets. It is possible that coexistence of these two disease entities and unrecognized IDD in patients with Mets might subsequently evaluate CVD risk. Moreover little is known about the relationship between IDD and the components of Mets. Thus the purpose of present study was to evaluate the pattern of IDD in patients with Mets and its relationship with components of Mets.
Methods - A total 204 diagnosed patients with Mets were recruited in the study. The thyroid function test parameter were measured to classify IDD at Chattrapati Shivaji Hospital, Subharti Medical College, Meerut, statistical analyses were performed using SSPSS version 16.0 to evaluated pattern and relationship.
Result - The overall prevalence of IDD in patients with Mets and components of Mets although there was significant difference in waist circumference of three groups of IDD. [Hypo, Hyper and subclinical thyroid disorders].
Conclusion - Present study concludes that patients with Mets had higher subclinical hypothyroidism. Although there was no evidence of any association between IDD status and all components of Mets. The IDD should be considered when evaluating and treating patients of Mets to minimize the risk.