Status of Dyslipidemia Management with Statins, in In-patients with known Coronary Artery Disease confirmed by angiographic findings

Authors

  • Vijay T Department of Pharmacology, Andhra medical college, Visakhapatnam http://orcid.org/0000-0001-9801-2461
  • Baruah DK Department of Cardiology, Apollo Hospitals, Visakhapatnam
  • Ushakiran P Department of Cardiology, Apollo Hospitals, Visakhapatnam
  • Sudha J Department of Cardiology, Apollo Hospitals, Visakhapatnam
  • Sudhakar K Department of Cardiology, Apollo Hospitals, Visakhapatnam
  • Srinivas A. Department of Cardiology, Apollo Hospitals, Visakhapatnam

DOI:

https://doi.org/10.7439/ijbr.v8i7.4248

Abstract

Aim: To determine the status of dyslipidemia management with statins in In-patients with known Coronary Artery Disease (CAD) confirmed by angiographic findings. Methods: This study has been conducted in a corporate cardiac centre at Visakhapatnam, Andhra Pradesh. This study is a retrospective analysis of data collected from the electronic medical records in terms of age, sex, CAD status, associated risk factors, statin usage, and lipid parameters. Results: Among a sample of 92 known CAD in-patients, 81.5% achieved LDL-C goal of 100 mg/dl as recommended by Third Report of the National Cholesterol Education Program (NCEP) Adult Treatment Panel III [ATP III] for CAD and CAD risk equivalents. Success rates among males and females are 79.7% and 85% respectively. 78.2% of 69 patients on Atorvastatin, 85% of 20 patients on Rosuvastatin and 100% of 3 patients on Simvastatin achieved LDL-C goal. If the target LDL-C level is kept at 70 mg/dl as defined as optional goal for very high risk CAD and CAD risk equivalents, the success rate is only 31.5%. Conclusion: The Success rates for achieving LDL-C goals ( 100mg/dl) is satisfactory in this facility. But the major concern in this study is even with desired LDL-C levels 61% of these in-patients suffered with a recurrent CAD leaving an opportunity to reconsider the target LDL-C to still lower levels ( 70 mg/dl) which is mentioned just as an optional for very high risk candidates in NCEP ATP-III guidelines.

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Author Biography

  • Vijay T, Department of Pharmacology, Andhra medical college, Visakhapatnam

    Clinical Pharmacologist,

    Department of Clinical Pharmacology

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Published

2017-07-28

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Original Research Articles

How to Cite

1.
Status of Dyslipidemia Management with Statins, in In-patients with known Coronary Artery Disease confirmed by angiographic findings. Int Jour of Biomed Res [Internet]. 2017 Jul. 28 [cited 2024 Oct. 18];8(7):420-4. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/4248