Foetal Cord Serum Prolactin: Levels and Association in Complications of pregnancy and Respiratory Distress Syndrome (RDS)

Authors

  • Bhupendra Patil Assistant Professor, Department of Obstetrics and Gynecology, Govt. Medical College, Akola, Maharashtra
  • Vilas Malkar Shri Vasantrao Naik Government Medical College, Yavatmal, Maharashtra
  • Vivek Karale Assistant Professor, Department of Obstetrics and Gynecology, Govt. Medical College, Akola, Maharashtra, India
  • Madhuri Ugalmugle Senior Resident, Department of Obstetrics and Gynecology, Govt. Medical College, Akola, Maharashtra
  • Suwarna Patil Associate Professor, Department of Pathology, Govt. Medical College, Akola, Maharashtra

DOI:

https://doi.org/10.7439/ijbr.v7i5.3245

Abstract

The study was carried on 85 newborns to establish a relationship between umbilical cord serum prolactin levels and gestational age, neonatal lung function and maternal complication. Serum cord prolactin level increased from 166.33ng/ml to 379.36ng/ml from 24 to 42 weeks of gestation. A significant association was demonstrated between cord serum prolactin level and birth weight (P 0.001). Newborns that developed RDS had a significant low level of serum prolactin (207.09 ng/ml) as compared to that of non-RDS newborns. The newborns with Apgar score of 7 or less had significantly lower serum prolactin levels than those with Apgar score more than 7 (235.36 ng/ml Vs. 357.05 ng/ml). There was a significant difference between prolactin levels of newborns in normal and abnormal pregnancy (414.61 ng/ml Vs. 312.44ng/ml). Newborns of mothers with PIH had lower prolactin levels as compared to normal (322.67 ng/ml Vs. 414.67 ng/ml). The risk of RDS is less in newborn with high prolactin level than in newborns with low prolactin levels. So prolactin might have a role in fetal lung maturation.

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Author Biography

  • Vilas Malkar, Shri Vasantrao Naik Government Medical College, Yavatmal, Maharashtra

    Assistant Professor

    Dept. of Community Medicine

References

Clinical Gynecologic Endocrinology and Infertility, Speroff. 7th Ed. Part I: Chapter 1, 2, 5, 6, 16.

Dayal M., Malhotra K., Mukherjee K., Verma M. Fetal cord prolactin in normal and abnormal pregnancies. Obstet Gynecol. Ind. 2001 May; 51(3):86-89

Jindal Promila, Singh Daljit, Goyal Anupama. Fetal cord serum level in normal and abnormal pregnancies. Obstet Gynecol. Ind. 2005 Sept; 55(5): 419-423.

Tolino A, de Conciflis B, Romano L, Graziano E. Fetal prolactin, levels and. respiratory distress syndrome. Clin Exp Obstet Gynecol. 1983; 10(4):198-200.

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Published

2016-05-30

Issue

Vol. 7 No. 5 (2016): May

Section

Original Research Articles

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How to Cite

1.
Foetal Cord Serum Prolactin: Levels and Association in Complications of pregnancy and Respiratory Distress Syndrome (RDS). Int Jour of Biomed Res [Internet]. 2016 May 30 [cited 2026 Mar. 29];7(5):256-9. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/3245