A randomized trial of Intraarticular bupivacaine and bupivacaine with clonidine for postoperative analgesia after arthroscopic knee surgery

Authors

  • Neeta Verma Datta Meghe Institute of Medical Sciences
  • Kaurna Taksande Datta Meghe Institute of Medical Sciences
  • Devavrat Vaishnav Datta Meghe Institute of Medical Sciences

DOI:

https://doi.org/10.7439/ijbr.v7i3.3089

Abstract

Alpha-2-adrenergic agonists have peripheral analgesic effect, We have assessed the potential analgesic effect of intraarticular clonidine after intraarticular administration in arthroscpic knee surgery. Intraarticular (IA) local anaesthetics are often used for the management and prevention of pain after artheroscopic knee surgery. Clonidine an ?2 agonist prolongs the duration of local anaeshtetics. We designed this study to determine whether clonidine added to an IA injection would result in an analgesic benefit. We evaluated 60 patients undergoing arthroscopic knee surgery under spinal anaesthesia. After surgery patients were randomly assigned into two groups. Group B received 20ml of 0.25% bupivacine IA. Group C received 20ml of 0.25 bupivacaine along with 1g/kg BW of clonidine. The study revealed a significant difference in analgesia from the IA administration of clonidine. Patients in group C had a significantly decreased need for postoperative analgesia and increased analgesic duration.

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Author Biographies

  • Neeta Verma, Datta Meghe Institute of Medical Sciences
    Assistant professor Dept of Anaesthesia Jawaharlal Nehru Medical college Wardha Sawangi (MH)
  • Kaurna Taksande, Datta Meghe Institute of Medical Sciences
    Associate professor Dept of Anaesthesia Jawaharlal Nehru Medical college Wardha Sawangi (MH)
  • Devavrat Vaishnav, Datta Meghe Institute of Medical Sciences
    Resident Dept of Anaesthesia Jawaharlal Nehru Medical college Wardha Sawangi (MH)

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Published

2016-03-30

Issue

Vol. 7 No. 3 (2016): Mar

Section

Original Research Articles

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How to Cite

1.
A randomized trial of Intraarticular bupivacaine and bupivacaine with clonidine for postoperative analgesia after arthroscopic knee surgery. Int Jour of Biomed Res [Internet]. 2016 Mar. 30 [cited 2024 Oct. 18];7(3):144-6. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/3089