A study of fusion of cervical vertebrae- C2 with C3

Abstract

Background: Congenital anomalies are common in the vertebral column. In condition of fusion of the cervical vertebrae, two vertebrae appear not only structurally as one but also function as one. This fusion may be congenital or acquired. Vertebral fusion anomalies are likely to be associated with disturbance of Pax-1 gene expression in the developing vertebral column. Aims and Objectives: The present study is to study the fused C2 with C3 vertebrae and its clinical importance. Materials and Methods: The present study conducted on 75 dry adult human axis (C2) vertebrae of either sex in the Department of Anatomy, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, India. The fused C2 with C3 was found and carefully studied. Results: In the present study the incidence of fused C2 with C3 is 1.33% (1out of 75). Conclusion: Fusion of C2 C3 clinically important to rule out various syndromes; Klippel-feil syndrome, Crouzons syndrome, which causes abnormalities of the neck movements with shortening of spine in the cervical region. Congenital Fused Congenital Vertebrae is one of the primary malformation of chorda dorsalis. Awareness of anomalies of cervical vertebrae is of great importance to anatomists, orthopaedicians, neurologists, neurosurgeons and even orthodontists. Also anaesthetists must be aware of these anomalies while doing endotracheal intubation, where extension of the neck is done.