DNA damage in a patient with Systemic Lupus Erythematosus and Nephropathy- A Case Report

Authors

  • Gurleen Kaur Tung Department of Human Genetics Guru Nanak Dev University, Amritsar-143005
  • Gursatej Gandhi Department of Human Genetics Guru Nanak Dev University, Amritsar-143005

DOI:

https://doi.org/10.7439/ijbr.v6i7.2213

Abstract

Objectives: Systemic Lupus Erythematosus (SLE) is a complex, multisystem autoimmune inflammatory disease. The inflammatory response in SLE exacerbates oxidative stress which tends to promote lipid peroxidation, protein oxidation and damage to DNA. Documentation of manifestation of DNA damage in SLE patients is scarce and related studies have not come to attention from this part of the world, therefore the present study showcases a case report on SLE. Methods: Assessment of DNA damage in peripheral blood leukocytes and oxidative stress biomarkers in blood sera of a 12y-old male presenting with SLE and nephropathy (on dialysis therapy) was made. Results:

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Published

2015-07-30

Issue

Vol. 6 No. 7 (2015): Jul

Section

Case Report

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How to Cite

1.
DNA damage in a patient with Systemic Lupus Erythematosus and Nephropathy- A Case Report. Int Jour of Biomed Res [Internet]. 2015 Jul. 30 [cited 2025 Mar. 12];6(7):527-30. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/2213