Analytical study of effects of intravenous lignocaine on pressor response during laryngoscopy and intubation

Authors

  • Kaleem Siddiqui M A Assistant Professor, Department of Anesthesiology, RIMS, Raichur
  • Kiran N Associate Professor, Department of Anesthesiology, RIMS, Raichur

DOI:

https://doi.org/10.7439/ijbr.v6i2.1670

Abstract

Induction of general anaesthesia and endotracheal intubation for maintenance of airway and prevention of aspiration is carried out frequently by the anaesthesiologist in day to day practice. This study was aimed to study the effects of Magnesium suplhate on pressor response during laryngoscopy and intubation. It was carried out in 50 patients of both sexes, between the age group of 20-60 years, belonging to ASA physical status grade I and II. 2% preservative free lignocaine 1.5mgKg-1 diluted to 10ml over a period of one minute given intravenously before inbutation resulted in tachycardia after intubation. But at the end of 5 minutes, the heart rate was still higher in lignocaine group. We found out that intravenous lignocaine is less effective to attenuate the pressor response and a better alternative should be used after further comparative studies.

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References

WJ Russell, Morris, Frewin et al : Changes in plasma catecholamine concentrations durin endotracheal intubation. British Journal of ANaesthesia 1981: 53:837-839.

Derbyshire D.R. Chmielewski A. Fell D et al : Plasma catecholamine responses to tracheal intubation. British Journal of Anaesthesia 1983, 55: 855-860.

Bedford Robert, Barney : Hospital admission blood pressure: A prediction for hypertension following endotracheal intubation : Anesth. Analg, 1980 : 59:367-370.

Prys Roberts, Greene, Meloche et al : Studies of anaesthesia in relation to hypertension , II : Haemodynamic consequences o induction and endotracheal intubation. British Journal of Anaesthesia, 1971:43:531-546.

G Lavies, Meiklejohn, May et al : Hypertensive and catecholamine response to tracheal intubation in patients with pregnancy included hypetension. British Journal of Anaesthesia 1989: 63:429-434.

Mudit Kumar, Tikle : Attenuation of vardiovascular responses to larytngoscopy and tracheal intubation with metoprolol. Indian Journal of Anaesthesia 1995; 43:385-388.

SC Kolli, R Misra, M Misra et al : Use of verapamil for preventing tachycardia and hypertension in response to laryngoscopy and intubation in treated hypertensive patients. Indian Journal of Anaesthesia 1987; 35:271-276.

K Mikawa, K Nishina, Maekawa et al : Comparison of nicardipine, diltizzen and verapamil for controlling the cardiovascular responses to tracheal intubation. British Journal of ANaesthesia; 1996; 76:221-226.

C Crawford D Fell, Achola et al : Effects of alfentanil on the pressor and catecholamine responses to tracheal intubation. British Journal Of Anaesthesia; 1987, 59 : 707-712.

Ruchi, Baljit, Lalita : A double blind study of attenuation on cardiovascular respnses to tracheal intubation; Intravenous buprenorphine Vs. Placebo. Asian archieves of Anaestnesiology and Resuscitation ; 1995; XLII/1: 27-31.

J Wing, A Bajaj, R.P. Sapru : Isosorbide dinitrate spray attenuation of cardiovascular responses to laryngoscopy and intubation. Anesthesia 1992; 47 : 523-526.

Abou Madi M N, Keszler H, Yacoub : Cardiovascular reactions to laryngoscopy and tracheal intubation following small and large intravenous dose of lignocaine. Canadian ANaesthetic Society Journal 1977; 24:12 -19.

Robert K.Stoelting : Blood pressure and heart rate changes during short duration laryngoscopy for tracheal intubation: Influence of viscous or intravenous lidocaine. Anesth Analg 1978;57:197-199.

Charemmr, Flemming, Jens, et al : Lack of effect of intravenous lidocaine on hemodynamic responses to rapid sequence induction of general anaesthesia; a double blind controlled clinical trial. Anest. Analg 1986: 65:1037-1041.

Charles, Vern, Gerald et al : Effects of aerosolized and / or intavenous lidocaine on hemodynamic responses to laryngoscopy and intubation in outpatients. Anaest. Analg, 1988; 67:389-392.

C D Miller and Warren : I V lignocaine ails to attenuate the cardiovascular response to laryngoscopy and tracheal intubation. British Journal of Anaestheia; 1990, 65: 216-219.

Stanley Tam, Chung, Campbell : Intravenous lidocaine: Optimal time of injection before tracheal intubation. Anaesthesia Analg 1987; 66:1036-1038.

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Published

2015-02-28

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Section

Original Research Articles

How to Cite

1.
Analytical study of effects of intravenous lignocaine on pressor response during laryngoscopy and intubation. Int Jour of Biomed Res [Internet]. 2015 Feb. 28 [cited 2026 Mar. 29];6(2):104-7. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/1670