Synthesis and characterization of some novel indole based 1,3,4-oxadiazoles with antimicrobial activity

Authors

  • Lingaiah Nagarapu Lab-6, Main building, Indian Institute of Chemical Technology, Hyderabad, Telangana
  • Upendra Pingili Lab-6, Main building, Indian Institute of Chemical Technology, Hyderabad, Telangana

DOI:

https://doi.org/10.7439/ijbr.v5i11.805

Keywords:

Biceps Brachii, Pronator Teres, Variation, Compression syndrome

Abstract

A novel series of various 1-[5-(1 H -indol-3-ylmethoxymethyl)-2-phenyl-[1,3,4]oxadiazol-3-yl]-ethanone and its derivatives (5a-f) were synthesized from (1 H -indol-3-ylmethoxy)-acetic acid-benzylidene-hydrazide and its derivatives (4a-f) by using (1 H -indol-3-yl)-methanol (1) as raw material and including (1 H -indol-3-ylmethoxy)-acetic acid ethyl ester (2) and (1 H -indol-3-ylmethoxy)-acetic acid hydrazide (3) as intermediates. The chemical structures of all these compounds have been entrenched by IR, 1 H and 13 C-NMR, mass spectral data and elemental analysis. The newly synthesized compounds have been used to find their potential in order to achieve the antibacterial and antifungal activities.

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Published

2014-11-30

Issue

Vol. 5 No. 11 (2014): Nov

Section

Original Research Articles

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How to Cite

1.
Synthesis and characterization of some novel indole based 1,3,4-oxadiazoles with antimicrobial activity. Int Jour of Biomed Res [Internet]. 2014 Nov. 30 [cited 2025 Mar. 13];5(11):681-4. Available from: https://ssjournals.co.in/index.php/ijbr/article/view/1107