A review on Ethogel for topical application
Keywords:
Ethogel, Vescular System, Nano-Gel, Topical Drug Delivery SystemAbstract
Topical drug delivery remains a challenging field due to the barrier nature of the skin (especially the stratum corneum). Vesicular systems such as ethosomes have emerged as promising nanocarriers for improved dermal/ transdermal delivery. When such ethosomal suspensions are incorporated into gel bases, the resultant formulations are termed “ethogel” (or nano‐ethogel) and offer advantages of enhanced skin permeation, deposition, sustained release and better patient compliance. This review critically examines the formulation science of ethogel, its mechanisms of action, evaluation parameters, applications (especially in dermatology and oncology), formulation challenges, regulatory and translational aspects, and future prospects.
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