Anti-ulcer potential of the Ethanolic Extract of leavesof Solanum Violaceum in Wistar albino rats
Keywords:
Solanum violaceum, Ethanol, Indomethacin, Omeprazole, RanitidineAbstract
The study evaluates the possible gastro protective of Ethanolic extract of leaves of Solanum violaceum [EESV] using two different gastric ulcer models. Gastric ulcers in Wistar albino rats were induced by Ethanol (1ml/200gm) and Indomethacin (30mg/kg) induced ulcer. Various parameters like Ulcer index, Acid volume, Total acidity, pH, Total protein, Glutathione, Catalase and Superoxide dismutase were evaluated. Omeprazole (20mg/kg) and Ranitidine (60mg/kg) was used as the standard drug. Solanum violaceum was administered at two dose levels, 250 mg/kg and 500 mg/kg body weight. Statistical analysis was done by ANOVA followed by Dunnet
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