Anti-ulcer potential of the Ethanolic Extract of leavesof Solanum Violaceum in Wistar albino rats

Authors

  • Mamatha B. S. Department of Pharmacology, Bharathi College of Pharmacy, Bharathinagara, Mandya-571422 Author
  • Palaksha M. N. Associate Professor and HOD of Department of Pharmacology, Bharathi College of Pharmacy, Bharathinagara, Mandya-571422 Author
  • Nandini K. N. Department of Pharmacology, Bharathi College of Pharmacy, Bharathinagara, Mandya-571422 Author
  • Lekhana A. R. Department of Pharmacology, Bharathi College of Pharmacy, Bharathinagara, Mandya-571422 Author

Keywords:

Solanum violaceum, Ethanol, Indomethacin, Omeprazole, Ranitidine

Abstract

The study evaluates the possible gastro protective of Ethanolic extract of leaves of Solanum violaceum [EESV] using two different gastric ulcer models. Gastric ulcers in Wistar albino rats were induced by Ethanol (1ml/200gm) and Indomethacin (30mg/kg) induced ulcer. Various parameters like Ulcer index, Acid volume, Total acidity, pH, Total protein, Glutathione, Catalase and Superoxide dismutase were evaluated. Omeprazole (20mg/kg) and Ranitidine (60mg/kg) was used as the standard drug. Solanum violaceum was administered at two dose levels, 250 mg/kg and 500 mg/kg body weight. Statistical analysis was done by ANOVA followed by Dunnet

Downloads

Download data is not yet available.

Downloads

Published

30-03-2020

Issue

Section

Research Articles

How to Cite

1.
S. MB, N. PM, N. NK, R. LA. Anti-ulcer potential of the Ethanolic Extract of leavesof Solanum Violaceum in Wistar albino rats. Int J of Adv in Sci Res [Internet]. 2020 Mar. 30 [cited 2025 Mar. 14];6(3):e5396. Available from: https://ssjournals.co.in/index.php/ijasr/article/view/5396