Hepatitis C - Challenges and New Approaches in Vaccine Development

Authors

  • Almas Shamaila Bioviz technologies Pvt Ltd Author
  • Madhavi Chandra Bioviz Technologies Pvt Ltd, Hyderabad Author
  • Khaja MN Bioviz Technologies Pvt Ltd, Hyderabad Author

Keywords:

Hepatitis C, Vaccine, Antibodies, T cell response

Abstract

Hepatitis C continues to be the serious global health treat and hundreds of people die every year due to liver failure. Hepatitis C Virus, the virus that that won the battle with no vaccine till date to beat its survival. Despite 15 years of its discovery, no vaccine has come up eradicate the virus. The high genetic diversity and the resistant nature of the virus is halting the progress towards vaccine development however many promising new antiviral drugs are in clinical trials giving a hope that in the coming years a successful vaccine will be developed. Many approaches like inducing neutralising antibody, inducing T cell response, development of Direct Acting Antivirals and drugs targeting host proteins are being tried out for the development of a safe and effective vaccine for Hepatitis C, some of which are discussed in this review.

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Published

31-07-2019

Issue

Vol. 5 No. 7 (2019): Jul

Section

Review Articles

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How to Cite

1.
Shamaila A, Chandra M, MN K. Hepatitis C - Challenges and New Approaches in Vaccine Development. Int J of Adv in Sci Res [Internet]. 2019 Jul. 31 [cited 2026 Jan. 3];5(7):e2566. Available from: https://ssjournals.co.in/index.php/ijasr/article/view/2566