Estimation of Ampicillin trihydrate in bulk and formulation by first order derivative area under curve UV-spectrophotometric methods

Authors

  • Audumbar Digambar Mali Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Ritesh Bathe Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Ashpak Tamboli Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author

DOI:

https://doi.org/10.7439/ijasr.v1i5.2061

Keywords:

Ampicillin Trihydrate, First order Derivative, Area under Curve, AUC

Abstract

Simple, fast and reliable spectrophotometric methods were developed for determination of Ampicillin Trihydrate in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in Methanol. The quantitative determination of the drug was carried out using the second order Derivative Area under Curve method values measured at 224-231nm. Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of Ampicillin Trihydrate using 5-25μg/ml (r

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Author Biography

  • Audumbar Digambar Mali, Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra
    Pharmaceutics

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Published

30-06-2015

Issue

Vol. 1 No. 5 (2015): IJASR

Section

Research Articles

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How to Cite

1.
Mali AD, Bathe R, Tamboli A. Estimation of Ampicillin trihydrate in bulk and formulation by first order derivative area under curve UV-spectrophotometric methods. Int J of Adv in Sci Res [Internet]. 2015 Jun. 30 [cited 2025 May 24];1(5):239-43. Available from: https://ssjournals.co.in/index.php/ijasr/article/view/2061
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