Estimation of Tramadol Hydrochloride in Bulk and Formulation by Second Order Derivative Area Under Curve UV-Spectrophotometric Methods.

Authors

  • Rekha Kharat Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Santosh Jadhav Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Shivaji Shinde Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Seemarani Pawar Department of Pharmaceutical chemistry, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Ashpak Tamboli Department of Pharmaceutical chemistry, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author

DOI:

https://doi.org/10.7439/ijasr.v1i7.1989

Abstract

Simple, fast and reliable spectrophotometric methods were developed for determination of Tramadol Hydrochloride in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in Distilled Water. The quantitative determination of the drug was carried out using the second order Derivative Area under Curve method values measured at 272-280nm. Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of Tramadol Hydrochloride using 2-10μg/ml (r

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Published

03-09-2015

Issue

Vol. 1 No. 7 (2015): IJASR

Section

Research Articles

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How to Cite

1.
Kharat R, Jadhav S, Shinde S, Pawar S, Tamboli A. Estimation of Tramadol Hydrochloride in Bulk and Formulation by Second Order Derivative Area Under Curve UV-Spectrophotometric Methods. Int J of Adv in Sci Res [Internet]. 2015 Sep. 3 [cited 2026 Feb. 15];1(7):308-12. Available from: https://ssjournals.co.in/index.php/ijasr/article/view/1989
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