Zero Order and Area Under Curve Spectrophotometric methods for determination of Omeprazole Capsules in Pharmaceutical Formulation

Authors

  • Santosh Balaso Jadhav Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Rekha Kharat Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade,Sangola-413307, Solapur, Maharashtra Author
  • Farhat Mujawar Pirjade Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade,Sangola-413307, Solapur, Maharashtra Author
  • Dilshadbe Tamboli Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade,Sangola-413307, Solapur, Maharashtra Author

DOI:

https://doi.org/10.7439/ijasr.v1i2.1854

Keywords:

Omeprazol, UV visible spectrophotometry, AUC, Method Validation

Abstract

Simple, fast and reliable spectrophotometric methods were developed for determination of Omeprazole in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in Methanol. The quantitative determination of the drug was carried out using the zero order derivative values measured at 303 nm and the area under the curve method values measured at 300-305 nm (n=2). Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of Omeprazole using 2-10μg/.ml (r

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Author Biography

  • Santosh Balaso Jadhav, Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra
    pharmaceutics

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Published

30-03-2015

Issue

Vol. 1 No. 2 (2015): IJASR

Section

Research Articles

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How to Cite

1.
Jadhav SB, Kharat R, Pirjade FM, Tamboli D. Zero Order and Area Under Curve Spectrophotometric methods for determination of Omeprazole Capsules in Pharmaceutical Formulation. Int J of Adv in Sci Res [Internet]. 2015 Mar. 30 [cited 2025 May 20];1(2):102-7. Available from: https://ssjournals.co.in/index.php/ijasr/article/view/1854
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