Zero Order and Area Under Curve Spectrophotometric methods for determination of Oxcarbazepine in Pharmaceutical Formulation

Authors

  • Santosh Balaso Jadhav Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author
  • Nilesh Patil Department of Pharmaceutical Chemistry, Appasaheb Birnale College of Pharmacy, Sangli, Maharashtra Author
  • Ashpak Tamboli Department of Pharmaceutical Chemistry, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra Author

DOI:

https://doi.org/10.7439/ijasr.v1i3.1780

Keywords:

Oxcarbazepine, UV visible spectrophotometry, AUC, Method Validation

Abstract

Simple, fast and reliable spectrophotometric methods were developed for determination of Oxcarbazepine in bulk and pharmaceutical dosage forms. The solutions of standard and the sample were prepared in Distilled Water. The quantitative determination of the drug was carried out using the zero order derivative values measured at 256 nm and the area under the curve method values measured at 252-258 nm (n=2). Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of Oxcarbazepine using 5-25 μg/ml (r

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Author Biography

  • Santosh Balaso Jadhav, Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade, Sangola-413307, Solapur, Maharashtra
    pharmaceutics

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Published

10-04-2015

Issue

Section

Research Articles

How to Cite

1.
Jadhav SB, Patil N, Tamboli A. Zero Order and Area Under Curve Spectrophotometric methods for determination of Oxcarbazepine in Pharmaceutical Formulation. Int J of Adv in Sci Res [Internet]. 2015 Apr. 10 [cited 2026 Mar. 10];1(3):156-61. Available from: https://ssjournals.co.in/index.php/ijasr/article/view/1780