Liquisolid Compacts: A Review
DOI:
https://doi.org/10.7439/ijap.v6i7.4056Keywords:
Cassia siamea, antihyperglycemia, Diabetes, kidney functionAbstract
Solubility is a major problem for nearly one third drugs in their development phase. Liquisolid technique is a most promising technique for promoting dissolution by increase in solubility. Liquisolid compact technology is a novel concept for oral drug delivery. Liquisolid compact technology was first described by spireas et.al. (1998). According to the new formulation method of liqui-solid compacts, liquid medications such as solutions or suspensions of water insoluble drugs in suitable nonvolatile liquid vehicles can be converted into acceptably flowing and compressible powders by blending with selected powder excipients.Downloads
References
. Spireas, S. Liqui-solid systems and methods of preparing same. U.S. Patent 6423339B1 (2002)
. Spireas, S., Sadu, S. Enhancement of prednisolone dissolution properties using liqui- Solid compacts. Int. J. Pharm. 1998; 166: 177-88.
. Yadav, V., Yadav, A., Bhise, S.,
. Kulkarni Ajit S., Aloorkar Nagesh H., Mane Madhav S. and Gaja Jayashree B., Liqui-solid Systems. Int.J of Pharma. Sci. and Nanotechnology, 2010; 3(1):795-802.
. Bindu MB, Kusum B and David Banji, Novel Strategies for Poorly Water Soluble Drugs, International Journal Of Pharmaceutical Sciences Review and Research,2010; 4(3): 1-5.
. Sharma, A., Jain, C.P. Techniques to enhance solubility of poorly soluble drugs: a review. J. Global Pharm. Tech. 2010; 2: 18-28.
. Saharan. , Kukkar V., Kataria, M., Gera, M., Choudhury P., Dissolution enhancement of drugs. Part I: technologies and effect of carriers. Int. J. Health Res. 2009; 2: 107-124.
. Rakesh P. Patel, Jagrut H. Dhruv,Bnkimchandra J. Bhatt, Ajay. M. Suthar.Formulation development and optimization of Cefditoren pivoxil dispersible tablet, International Journal of Current Pharmaceutical Research, 2010; 2(1): 20-25.
. Ravi Kumar, Swati Patil M B Patil, Sachin R.Patil, Mahesh S. Paschapur. Formulation evaluation of mouth dissolving tablets of Fenofibrate using sublimation technique, Int J Chem Tech Res., 2009; 1(4): 840-850.
. Khattab, I., (1989) in
. Spireas, S., Liquisolid systems and methods of preparing the same. Pharmaceutical patent, 6423339, July 23, (2002).
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).