Phytochemical Investigation and Analgesic Activity of Calotropis Procera
Keywords:
Calotropis procera, Pain, Analgesic Activity, Ethanolic Extract, PentazocineAbstract
The acute toxicity study revealed safely of the extract up to a dose of 2000 mg/kg in mice. The ethanolic, petroleum ether and chloroform extract of leaves of C. procera at a dose of 100, 200 and 500 mg/kg was selected for analgesic activity. Different extracts (Petroleum ether, chloroform and ethanolic. of leaves of C. Procera were investigated for analgesic activity by using different models. The analgesic properties were studied on acetic acid induced writhing and tail flick latent period in rats. The result shows that the ethanolic extract of the leaves of C. procera was found to be effective.
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