Phytochemical and pharmacological evaluation of some medicinal plants against Enterovirus Type-I
Keywords:
Antiviral, Syzygium aromaticum, Costus speciosus, Plantago ovata, Thymus vulgaris, BioassayAbstract
The present study focused on the evaluation of antiviral activity of extracts from selected medicinal plants-Syzygium aromaticum (Clove), Costus speciosus (Costus), Plantago ovata, and Thymus vulgaris (Thyme)-against Enterovirus type 1 using RD cell models. This study supports the role of clove, plantago, and thyme as natural antiviral candidates, bridging traditional medicinal knowledge with modern drug discovery. They represent a valuable starting point for the development of cost-effective, safe, and broad-spectrum antiviral agents, particularly relevant in the face of emerging viral diseases.While the present investigation demonstrated promising antiviral activity of selected medicinal plants, several aspects require further exploration to establish their therapeutic potential:- Bioassay-guided fractionation should be carried out to isolate the specific phytoconstituents (e.g., flavonoids, phenols, tannins, terpenoids, saponins, mucilage) responsible for antiviral effects. Structural elucidation using advanced techniques such as HPLC, LC-MS, and NMR will help identify novel antiviral leads.
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