Pharmacognostic Standardisation, Formulation & Evaluation of Wheat grass and Vetiver Zizaniodes skin cream

Abstract

The work aims to perform the Pharmacognostic study of the leaves of the plant Triticum aestivum Linn., Family Poaceae, commonly known as ‘Wheatgrass’, and Vetiveria zizanioides (L.) Nash syn. Chrysopogon zizanioides (L.) Roberty or Vetiver (Family Poaceae). It is cultivated on a large scale all over India and occasionally in gardens. For the present study, samples of wheatgrass leaves were collected over a specific nine-day period. Herbal formulations have growing demand in the world market, and the plants have been reported in the literature to have good anti-microbial, anti-oxidant and anti-inflammatory activity. In this study cream was formulated based using herbal extracts and its evaluation. The evaluations of the formulation were done on different parameters like pH, spreadability, stability etc. Formulation F1 showed good spreadability, good consistency, and homogeneity with good appearance, pH, and no evidence of phase separation and ease of removal. The formulation F1 shows no redness, edema, inflammation, and irritation to the skin during irritancy studies. These studies suggest that the composition of extracts and the base of cream of F3 is more stable and safer, and it may produce synergistic action. It can be concluded that a herbal cream without side effects, having antioxidant property can be used as provision of a barrier to protect the skin and avoid aging of the skin.