Formulation and Evaluation of Polyherbal Antimicrobial Gel
Keywords:
Neem, Turmeric, Aloe vera, Antimicrobial activityAbstract
Introduction: Neem (Azadirachta indica, Meliaceae), Turmeric (Curcuma longa L., Zingeberaceae), Aloe vera (Aloe barbadensis Miller, Liliaceae) are been used as traditional Ayurvedic medicine in India since ancient times. These herbal plants have been reported in the literature having good antimicrobial, anti-oxidant and anti-inflammatory activity. Herbal remedies are more acceptable in the belief that they have fewer side effects compared to synthetic ones.
Objective: The present research aimed to formulate and evaluate polyherbal antimicrobial gel containing Neem (Azadirachta indica, Meliaceae), Turmeric (Curcuma longa L., Zingeberaceae), Aloe vera (Aloe barbadensis Miller, Liliaceae).
Method: F1 and F2 formulation were prepared using varied concentration of extract and the control formulation prepared without extract. The Prepared formulations were evaluated for various parameters like colour, appearance, viscosity, pH, spreadability, washability, extrudability, skin irritation. Antimicrobial screening was performed and compared it with control formulation.
Result: The result of study shows that F1 and F2 show good antimicrobial property on E. coli micro-organism as compare to control formulation.
Conclusion: The developed polyherbal gel shows good antimicrobial property therefore it can be use in microbial infections of skin.
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