Formulation and Evaluation of Polyherbal Antimicrobial Gel

Authors

  • Viraj Dalal Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Nagpur 440037, Maharashtra
  • Shivan Bhonde Dadasaheb Balpande College of Pharmacy, Nagpur 440037, Maharashtra, India
  • Monali N. Dumore Department of pharmaceutical chemistry, Dadasaheb Balpande College of Pharmacy, Besa, Nagpur, Maharashtra https://orcid.org/0000-0001-5149-4053
  • Ujwala Mahajan Dadasaheb Balpande College of Pharmacy, Nagpur 440037, Maharashtra, India

Keywords:

Neem, Turmeric, Aloe vera, Antimicrobial activity

Abstract

Introduction: Neem (Azadirachta indica, Meliaceae), Turmeric (Curcuma longa L., Zingeberaceae), Aloe vera (Aloe barbadensis Miller, Liliaceae) are been used as traditional Ayurvedic medicine in India since ancient times. These herbal plants have been reported in the literature having good antimicrobial, anti-oxidant and anti-inflammatory activity. Herbal remedies are more acceptable in the belief that they have fewer side effects compared to synthetic ones.

Objective: The present research aimed to formulate and evaluate polyherbal antimicrobial gel containing Neem (Azadirachta indica, Meliaceae), Turmeric (Curcuma longa L., Zingeberaceae), Aloe vera (Aloe barbadensis Miller, Liliaceae).

Method: F1 and F2 formulation were prepared using varied concentration of extract and the control formulation prepared without extract.  The Prepared formulations were evaluated for various parameters like colour, appearance, viscosity, pH, spreadability, washability, extrudability, skin irritation. Antimicrobial screening was performed and compared it with control formulation.

Result: The result of study shows that F1 and F2 show good antimicrobial property on E. coli micro-organism as compare to control formulation.

Conclusion: The developed  polyherbal gel  shows good antimicrobial property therefore it can be use in microbial infections of skin.

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Published

2021-04-05

Issue

Section

Research Articles

How to Cite

1.
Formulation and Evaluation of Polyherbal Antimicrobial Gel. Int J of Phytopharm [Internet]. 2021 Apr. 5 [cited 2025 Mar. 14];10(6):e5566. Available from: https://ssjournals.co.in/index.php/ijpp/article/view/5566