DESIGN AND MICROBIAL SCREENING OF HERBAL OINTMENT OF Phyllanthus amarus
DOI:
https://doi.org/10.7439/ijpp.v4i4.96Abstract
Objective: Herbal medicines contribute in no small measure to health care the world over, especially for rural dwellers and developing countries. The extracts of Phyllanthus amarus have been reported to be medicinal. In this study, herbal ointment containing methanol extract of the aerial part of Phyllanthus amarus was formulated and evaluated for the pH and spreadability as well as its antimicrobial properties against some human pathogens: Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Aspergilus niger. Method: Pulverized dried leaves were extracted using methanol in ratio 1:4. Simple ointment BP was used as ointment base for dispersion of the plant extract. Parameters investigated include; spreadability, pH and zones of inhibition of extract and formulated ointment while chloramphenicol and fluconazole were used as controls. The sensitivity of the organisms in ointment containing varying concentrations of the extract was also determined. Result: The pH of the ointment was 6.17 0.9 and the spreadability was 120 0.5. B. subtilis, P. aeruginosa and staph aureus were susceptible to ointment containing 0.1% w/v and 0.15% w/v, while E. coli and A. niger were resistant. The organisms were all susceptible to the ointment containing 0.2% w/w P. amarus . Conclusion: P. amarus ointment has good antimicrobial properties and can be used for the treatment of wounds and skin infection caused by these organisms.Downloads
Download data is not yet available.
Downloads
Published
2014-09-01
Issue
Section
Research Articles
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
1.
DESIGN AND MICROBIAL SCREENING OF HERBAL OINTMENT OF Phyllanthus amarus. Int J of Phytopharm [Internet]. 2014 Sep. 1 [cited 2025 Mar. 14];4(4):113-6. Available from: https://ssjournals.co.in/index.php/ijpp/article/view/1194