Heparoprotective activity-A Review

Authors

  • Sowjanya Guduguntla Department of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, Rajampet, Andhra Pradesh,
  • D. Swarnalatha Department of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, Rajampet, Andhra Pradesh,
  • T. Shivakala Department of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, Rajampet, Andhra Pradesh,
  • Mobeena S. K. Department of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, Rajampet, Andhra Pradesh,

DOI:

https://doi.org/10.7439/ijpp.v3i2.50

Abstract

Liver diseases are a major problem of worldwide proportions and liver damage is very common since liver has the capacity to detoxicate toxic substances. In this review some of the plants with their extract studied for protective effect in liver diseases were summerised. The varios isolated compounds studied herein are Andrographolide, neo-andrographolide, bacoside-A, colchicine, populnin, naringenin, echinacoside, kolaviron, ternatin, indigtona, rubiadin, bacicalein, baicalin, wogonin, punicalagin, punicalin for their hepatoprotective activity. There are several chemicals have been known to induce heptotoxicity by producing reactive species which cause depletion in tissue thiol, lipid peroxidation, plasma membrane damage like carbontetrachloride, paracetomol, thioacetamide, antituberculer drugs, D galactosamine, liposachharide and arsenic etc.

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Author Biography

  • Sowjanya Guduguntla, Department of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, Rajampet, Andhra Pradesh,
    Pharmaceutical Chemistry,PGCET Rank:2085

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Published

2013-05-01

Issue

Vol. 3 No. 2 (2013): Mar-Apr

Section

Review Article

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How to Cite

1.
Heparoprotective activity-A Review. Int J of Phytopharm [Internet]. 2013 May 1 [cited 2025 Mar. 14];3(2):37-49. Available from: https://ssjournals.co.in/index.php/ijpp/article/view/1158