Phytochemicals and biological potentials of Calendula officinalis Linn: a review
Keywords:
Calendula officinalis, chemical compounds, bioactivitiesAbstract
Calendula officinalis is from the family of Asteraceae, commonly known as English Marigold or Pot Marigold is an aromatic herb which is used in Traditional system of medicine for treating wounds, ulcers, herpes, scars, skin damage, frost-bite and blood purification. It is mainly used because of its various biological activities to treat diseases as analgesic, anti–diabetic, anti-ulcer and anti-inflammatory. It is also used for gastro-intestinal diseases, gynecological problems, eye diseases, skin injuries and some cases of burn. Calendula oil is still medicinally used as, an anti-tumor agent, and a remedy for healing wounds. Plant pharmacological studies have suggested that Calendula extracts have antiviral and anti-genotoxic properties . Chemical studies have underlined the presence of various classes of compounds, the main being triterpenoids, flavonoids, coumarines, quinones, volatile oil, carotenoids and amino acids. The extract of this plant as well as pure compounds isolated from it, have been demonstrated to possess multiple pharmacological activities such as anti-HIV, cytotoxic, anti-inflammatory, hepatoprotective, spasmolytic and spasmogenic, amongst others.
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