Evaluation of Petrol fumes on Hepatic Enzymes activities in albino rats
Keywords:
Hepatic, Enzymes, Petrol, fumesAbstract
The study was carried out by exposing 35 albino rats divided into seven (7) groups of five (5) rats each to petrol fumes respectively at concentrations (Parts per Minute) of 0.00, 16,737 for 5 minutes daily , 20,240 for 10 minutes daily, 23,077 for 15 minutes daily, 27,344 for 20 minutes daily, 30,920 for 25 minutes daily and 34,458 for30 minutes daily for 21 days using a modified nose-inhalation exposure method. Alanine aminotransferase (ALT) and Aspartate aminotransferase(ALT) activities were determined by Reitman-Frankel method while Alkaline Phosphatase(ALK PHOS) activity was determined by Phenolphthalein Monophosphate Method. The data were subjected to statistical analysis using statistical package for social sciences (SPSS) version 21. There was significant difference (P<0.05) in Aspartate amino transferase (U/L) of 12.8
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