Effect of Vitamin B12 on Lipid Profile of albino rats infected with Trypanosoma brucei
Keywords:
Triglycerides, Cholesterol, High Density Lipoprotein, Low Density Lipoprotein, Trypanosoma bruceiAbstract
This study was carried out to determine the effect of vitamin B12 on the lipid profile of male Wistar albino rats infected with Trypanosomabruceibrucei. 24 male Wistar albino rats were divided into 6 groups namely; Control , Trypanosome infected, Diamenazene treated, 40mcg vitaminB12, 60mcg vitaminB12, 80mcg vitaminB12, The lipid profile indicators such as Triglycerides, Total cholesterol, High Density Lipoprotein and Low Density Lipoprotein were determined in all the albino rats using enzymatic methods while Low Density Lipoprotein was determined using Friedewald formula. The data was subjected to statistical analysis using SPSS version 20. The result showed a significant decrease (P<0.05) in the mean value ofTriglycerides (mg/dl), Cholesterol (mg/dl), HDL (mg/dl) and LDL (mg/dl) in trypanosome infected group (52.93
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