Is Homocysteine a silent marker for cardiovascular disease?

Authors

  • Nithin Varghese Abraham Father Muller Medical College, Mangalore 575002 , Karnataka
  • Priyanka S Bannikoppa Division of Nutrition, St. John’s Research Institute, St. John’s National Academy of Health Sciences, Bangalore 560034, Karnataka
  • Pauline Anand Department of Physiology , Father Muller Medical College, Man galore 575002 , Karnataka

DOI:

https://doi.org/10.7439/ijbar.v8i12.4515

Abstract

Background: Cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality in India. Association between hyperhomocysteinemia and Metabolic Syndrome (MS) or its components in a population with or without cardiovascular disease is not well established. This study aims to check levels of homocysteine (Hcy) and its relationship with CVD. Aims and Objectives: To check Hcy levels in healthy adults and MS patients to reflect its association with CVD. Material and Methods: Case control study was done on 40 subjects patients with MS (n=20) and controls (n=20) of 30 - 60 years at Fr. Muller Medical College Hospital, Karnataka. Results: Homocysteine levels were significantly higher in MS group when compared to controls (p = 0.04). Conclusion: MS group had higher homocysteine levels along with blood glucose, triglycerides, total cholesterol when compared to controls. Elevated levels of Hcy can be a marker for cardiovascular disease. Furthermore, the results of this study suggest the overall role of homocysteine function on insulin resistance, and its association with cardiovascular parameters.

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Published

2017-12-30

Issue

Vol. 8 No. 12 (2017): Dec

Section

Original Research Articles

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How to Cite

1.
Is Homocysteine a silent marker for cardiovascular disease?. Int J of Biomed & Adv Res [Internet]. 2017 Dec. 30 [cited 2024 Oct. 18];8(12):455-9. Available from: https://ssjournals.co.in/index.php/ijbar/article/view/4515