Phytochemical and pharmacological evaluation of hydroalcoholic extract of Lilium candidum for Anti-ulcer potential
DOI:
https://doi.org/10.7439/ijpr.v15i1.5863Keywords:
Anti-ulcer, Hydroalcoholic Extract, Lilium candidum, Phytochemical AnalysisAbstract
The present study with the hydroalcoholic flower extract of Lilium candidum (HELC) revealed that it has significant anti-ulcer activity. Usually, NSAIDs and corticosteroids are widely used in clinical practice as anti-inflammatory agents. Except for newer highly selective COX-2 inhibitors, NSAIDs and corticosteroids produce significant gastric irritation resulting in gastritis and gastric ulceration, especially on long-term treatment. The present study revealed that the HELC has ulcer-protective properties. Previous studies showed its potent anti-inflammatory activity. Therefore, it can be considered as an ideal substitute for conventional NSAIDs and glucocorticoids. Further studies have to be conducted to explain precisely the mechanism of action of this drug. It increased the healing of the indomethacin-induced ulcer.
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