Phytochemical and Pharmacological Evaluation of Bacopa monnieri for Anti- Arthritic Activity
DOI:
https://doi.org/10.7439/ijpr.v15i1.5862Keywords:
Bacopa monnieri, Rheumatoid Arthritis, Volatile Oil, HPTLC, NeutrophilsAbstract
Seven Sesquiterpenes were found, out of which five were hydrocarbons i.e. calarene, vardiflorene, α- panasinsen, α-santalene, γ- himachelene, one is ketonic i.e. jatamansoneand one is alcoholic i.e. epiglobulol; one Ttriterpene was observed i.e. unknown; among two others Ionol 4 (9.9%), 2,2,7,7- Tetramethyl tricyclo[6,2,1,0 (1,6)]undec-4-ene 3-one (1.7%) was observed. F-4 and F-7 extracts were found to be more stable and optimized than other formulations based on evaluation parameters. As a result, these can be investigated further for phytochemical analysis as well as in vitro and in vivo animal models against inflammation and rheumatoid arthritis.
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