A Cost Variation Analysis of Drugs used in the management of Thromboembolic Disorders- a pharmacoeconomic study.
Keywords:
Anti-platelets, Anti-coagulants, Fibrinolytics, Cost variation, Pharmaco-economicsAbstract
Background: Cardiovascular diseases (CVDs) have become a major cause of mortality among the Indians. The cost of anticoagulant, antiplatelet, and fibrinolytic drugs which are used to treat thromboembolic disorders and used as prophylactics for individuals at high risk of CVDs varies widely in Indian pharmaceutical market. Our aim of the study is to find different drugs available for managing thromboembolic disorders, either singly or in combination and to evaluate and compare the cost of a particular drug in the same strength, number, and dosage forms being manufactured by different companies.
Methods: The maximum cost and minimum cost of a particular drug in the same strength and dosage forms being manufactured by different companies was obtained from “current index of medical specialties” CIMS website The cost ratio and the percentage cost variation were noted for each brand.
Results: Amongst single drug therapy, Prasugrel 5mg showed highest price variation (4767.23%). Minimum cost variation was of Rivaroxaban 20mg (0%). In fixed dose combinations, highest cost variation was seen with Aspirin 75+ Clopidogrel 75mg (2770.96%) while minimum cost variation was of Aspirin 75mg + Prasugrel 10mg (8.52%).
Conclusions: There is lot of variation in prices of different brands of the same anticoagulants, fibrinolytics, and antiplatelet drugs available in Indian market. Hence, by reducing the cost variation and improving the affordability of drugs, we can improve compliance and adherence, the health status of community, and the economic burden due to healthcare expenditures.
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