Medhya activity profile of Kamala (Nelumbo nucifera Gaertn.) - An experimental study
Keywords:
Kamala, Nelumbo nucifera, behavioural models, MedhyaAbstract
Introduction: Kamala (Nelumbo nucifera Gaertn.) is an aquatic plant belonging to family Nymphaceae used among wide range of therapeutics, especially as Medhya (intellect promoter) in Indian system of medicine, since time immemorial. Hence present study is planned to substantiate the Medhya action of test drug in experimental animals.
Materials and Methods: Matured plant collected, shade dried, powder was taken for the study. 18 Wistar albino rats and 18 mice were selected and grouped into 3 groups with 6 rats/mice in control, standard and test groups. Gross behaviour test, open field behaviour test, spontaneous motor activity, Zero maze test, behavioural despair test and Mirror chamber test were conducted.
Results: In this experimental model test drug has shown potent antidepressant, anxiolytic and Nootropic action.
Discussion and Conclusion: Kamala (Nelumbo nucifera Gaertn.) best Medhya (intellect promoters) as per classical literature. Present study was conducted on animal models through behavioural studies, has proved it as promising antidepressant, anxiolytic and Nootropic herb.
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