Utilization and Adverse Drug Reactions of drugs in ophthalmic outpatient and inpatient department of a tertiary care hospital: A Pharmacoepidemiologial Study

Authors

  • Jyoti Gadhade Assistant Professor, Dept of Pharmacology, BJGMC Pune
  • Rajesh S Hiray Professor and HOD, Dept of Pharmacology, BJGMC Pune

Keywords:

Pharmacoepidemiology, Drug utilization research, Ophthalmology

Abstract

Introduction: Pharmacoepidemiology refers to the epidemiological methods to study the clinical use and effects of drugs in large number of people with the purpose of supporting the rational and cost effectiveness use of drugs.

Objective: To study the prescribing patterns of drugs in Ophthalmology and to evaluate prescriptions according to WHO Drug Use Indicators.

Materials& Methods: A cross sectional, observational study was conducted in the department of Ophthalmology. Data was collected from the prescriptions of patients in OPD & IPD. Various parameters of utilization pattern were evaluated.

Results: Total number of prescriptions analysed were 744 in which 2478 drugs were prescribed. Analysis of prescriptions showed that average number of drugs per prescription was 1.34 in OPD & 5.32 in IPD. The maximum number of drugs were prescribed in form of eyedrops (68.14%) in OPD and tablets(39.31%) in IPD. Majority of drugs in OPD were prescribed by brand name (61.22%) while in IPD majority were generic (61.75%).  Polypharmacy was commonly seen in IPD group (10.86%) as compared to OPD(0.20%) 83.97% of drugs from OPD and 93.08% from IPD were prescribed from National List of Essential Medicines. Average total cost per prescription was Rs 45.60 in OPD and Rs 20.04 in IPD. No adverse drug reactions were reported.

Conclusion: It is necessary to make prescribers aware about the importance prescribing and the factor of cost effectiveness in patients point of view. Also there is a need for the development of prescribing guidelines and educational initiatives to encourage the rational and appropriate use of drugs.

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Published

2021-03-30

Issue

Vol. 11 No. 3 (2021): Mar

Section

Research Articles

License

Copyright (c) 2021 International Journal of Pharmacological Research

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How to Cite

1.
Gadhade J, Hiray RS. Utilization and Adverse Drug Reactions of drugs in ophthalmic outpatient and inpatient department of a tertiary care hospital: A Pharmacoepidemiologial Study. Int J of Pharmc Res [Internet]. 2021 Mar. 30 [cited 2026 Jan. 26];11(3):e5580. Available from: https://ssjournals.co.in/index.php/ijpr/article/view/5580