In Vitro Antidiabetic Activity of Piper betel
Keywords:
Antidiabetic, ?-Amylase Inhibition, alfa-Glucosidase Inhibition, Haemoglobin Glucose Inhibition Assay, Piper betel, Traditional medicine, Yeast Glucose uptakeAbstract
Leaves of Piper betel possess several bioactivities and are used in traditional medicinal systems. However, its antidiabetic activity has not been scientifically investigated so far. The aim of this study, therefore, was to investigate the antidiabetic activity of Piper betel. An aqueous extract of the leaves was prepared and subjected to various in-vitro anti diabetic assays such as, In vitro Alpha Amylase Inhibition Assay, Yeast Glucose Uptake Assay, Alpha Glucosidase Enzyme Inhibition Assay, Haemoglobin Glucose Inhibition Assay. The aqueous extract proved to possess significant anti-diabetic activity All assays showed a maximum inhibition of either the enzyme or uptake of glucose into the cells. Thus, concluding that leaves of Piper betel possess significant antidiabetic activity.
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