Prevalence of Hepatitis B Virus Among Patients Receiving Multiple Blood Transfusions in Khartoum
Multiple Blood Transfusions
Keywords:
T. indica, hyperglycaemia food and water intake, hematologyAbstract
This study Aims to a determine the prevalence of HBs Ag in patient with multiple blood transfusion. In cross sectional study This cross sectional study 90 case. The age less than 60 years. with multiple transfusion, These study carried in Khartoum hospitals, Khartoum state from Sep. to Dec 2017, in the subjects serological test were done, ageless than 60 years. Detection of HBs Ag will be done by Elisa Kits. Results: A total number of 90 patients were screened during the study period. 55 (61.1%) were males and 35 (38.9%) were females. 11.1% of the patients were positive HBs Ag, HBV was more prevalent in age ( > 18 years, 18-25 years). Among HBsAg positive patients: 6 (60%) were males and 4(40%) were females. Four patients (11.8%) were HBs Ag positive and leukemia disease, two patients (11.1%) were HBs Ag positive and Sickle cell anemia, one patients (16.7%) was HBs Ag positive and Diamond blackfan anemia(DBA), Two patients HBsAg positive and suffer from bleeding after surgical operation. One patients were HBsAg positive and HCV positive, Four out of 13 (30.8%) were HBs Ag positive and jaundice positive, Two (28.6%) were HBs Ag positive and have family history of HBV. HBV transfusion transmission from occult HBV infection carrying extremely low viral loads is related to plasma volume transfused and possibly prevented by anti-HBs. HBV blood safety could be further improved by either anti-HBc screening (indicates previous or ongoing infection with hepatitis B virus in an undefined time frame).Downloads
Download data is not yet available.
References
1. Gaeta GB, Rapicetta M, Sardaro C, Spadaro A, Chionne F, Freni AM. Prevalence of anti-HCV antibodies in patients with chronic liver disease and its relationship to HBV and HDV infections. Infection. 1990;18:277–9. doi: 10.1007/BF01647003. [PubMed] [CrossRef]
2. Tsatsralt-Od B, Takahashi M, Nishizawa T, Endo K, Inoue J, Okamoto H. High prevalence of dual or triple infection of hepatitis B, C, and delta viruses among patients with chronic liver disease in Mongolia. J Med Virol. 2005;77:491–9. doi: 10.1002/jmv.20482. [PubMed] [CrossRef]
3. Parkj E , park . Hepatitis B virus infection in : park J , park m eds . Text book of preventive and social Medicine 15 thed Philadelphia ; w.B . saunders : 1996.p.145-47
4. Stephen B . james w . Hepatitis B virus in I daneil p , Abba I ,T , TristramG,eds. Basic and clinical immunology 8 thed. North walk san Maleocaifornia : Appeleton and log :1992. P464-72
5. Chisari FV, Ferrari: Hepatitis B virus immunopathogenesis Annu Rev IMMUNoI 13:29 – 60, 1995.
6. Alter H J, Hougthon M. Hepatitis C virus and elimination post transfusion hepatitis Natmed . 200. 6( 10 ) : 1082-1086
7. Wrighttl , MamishD, combs , etal . Hepatitis B virus and apparent fulminant non – A, non –Bhepatitis . Lancet 1992 339: 952
8. Alter M J, HADLERSC, Morgolis Hsietal The changing epidemiology of hepatitis B in the United States. Need for alternative vaccination strategies. JAMA1990: 263:1218.
9. Stephen B, James w. hepatitis B virus in daneil p ,Abbol , Terr. T , Tristrangeds .Basic and clinical immunology 98thed North walk san Maleocaifornia : Appeleton and long : 1992 .p 464-72
10. Philib A , BrunellA , hepatitis Binfed in : Beharnan RE ,Kliegman RM , Nelson WE , Vaughan vc ,eds . Nelsont Text book of paediatrics 14th ed . Philadelphia: saunders1992. P. 819 -22
11. Gohkt. Prevention and control & hepatitis B virus infection in signga pore . Ann Acadmedsingapore 1997: 26: 671.
12. Thompson N D, per z JF, Moor man AC, Holmberg SD. Non hospital health care. Associated hepatitis B and C virus transmission: United States 1998 -2008. Ann intern Med 2009. 150: 33.
13. Gerberdingj L. The infection health care provider. NEngijmed 1996 : 334 : 594
14. Dickson Rc, Everhart JE, lake JR, et al Transmission of hepatitis B by Transplantation of liver from donors positive for antibody to hepatitis B core antigen. Gastroenterology 1997 : 113: 1668
15. Wright l, Mamish D, combs c, et al. HEPATITIS B virus and apparent fulminant non .A, non – Bhepatitis . lancet 192 : 339: 952
16. Beasley RP, H wang LY, lincc,etal . Incidence & hepatitis Bvirus infection in preschool children in Taiwan. j infection D: S 1982 : 146 : 18.
17. Coursaget p, y vonnet B, chotard j , eta l . Age. and sex –related study of hepatitis B virus chronic carrier state in infants from endemic area ( Senegal) . j Med virol 1987 :22 :1.
18. Haber BA, Block J m, Jonas MM, et al Recommendations for screening, monitoring and referral of pediatric chronic hepatitis B pediatrics 2009; 124: e 1007
19. Krugmans, over by LR Mushahwarik, et al. Viral hepatitis type B studies on Natural history and prevention re-examined .N Engl J Med, 2000; 300:101.
20. Shepard CW, Finelli L, Alter MJ. Global epidemiology of Hepatitis C virus infection. Lancet Infect. Dis. 2005; 5: 558- 67.
21. 22. Badur S, Akgun A. Diagnosis of hepatitis B infections and monitoring of treatment. J Clin Virol 2001; 21: 229-237
22. 23. Allain JP. Occult hepatitis B virus infection. Transfus Clin Biol 2004; 11: 18-25
23. 24. Park K. Textbook of, preventive and social medicine. 20th ed. Jabalpur, India: Bhanot; 2009. 184- 94.
24. 25. Lt Col PK Gupta , Col H Kumar , Mr DR Basannar , Brig M Jaiprakash . Transfusion Transmitted Infections in Armed Forces : Prevalence and Trends :MJAFI ; 2006 ; 62 : 348– 350.
25. 26. Okoroiwu, H. U., Okafor, I. M., Asemota, E. A., Okpokam, D. C. (2018): Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation, BMC Public Health, vol 18(1), PP:645
2. Tsatsralt-Od B, Takahashi M, Nishizawa T, Endo K, Inoue J, Okamoto H. High prevalence of dual or triple infection of hepatitis B, C, and delta viruses among patients with chronic liver disease in Mongolia. J Med Virol. 2005;77:491–9. doi: 10.1002/jmv.20482. [PubMed] [CrossRef]
3. Parkj E , park . Hepatitis B virus infection in : park J , park m eds . Text book of preventive and social Medicine 15 thed Philadelphia ; w.B . saunders : 1996.p.145-47
4. Stephen B . james w . Hepatitis B virus in I daneil p , Abba I ,T , TristramG,eds. Basic and clinical immunology 8 thed. North walk san Maleocaifornia : Appeleton and log :1992. P464-72
5. Chisari FV, Ferrari: Hepatitis B virus immunopathogenesis Annu Rev IMMUNoI 13:29 – 60, 1995.
6. Alter H J, Hougthon M. Hepatitis C virus and elimination post transfusion hepatitis Natmed . 200. 6( 10 ) : 1082-1086
7. Wrighttl , MamishD, combs , etal . Hepatitis B virus and apparent fulminant non – A, non –Bhepatitis . Lancet 1992 339: 952
8. Alter M J, HADLERSC, Morgolis Hsietal The changing epidemiology of hepatitis B in the United States. Need for alternative vaccination strategies. JAMA1990: 263:1218.
9. Stephen B, James w. hepatitis B virus in daneil p ,Abbol , Terr. T , Tristrangeds .Basic and clinical immunology 98thed North walk san Maleocaifornia : Appeleton and long : 1992 .p 464-72
10. Philib A , BrunellA , hepatitis Binfed in : Beharnan RE ,Kliegman RM , Nelson WE , Vaughan vc ,eds . Nelsont Text book of paediatrics 14th ed . Philadelphia: saunders1992. P. 819 -22
11. Gohkt. Prevention and control & hepatitis B virus infection in signga pore . Ann Acadmedsingapore 1997: 26: 671.
12. Thompson N D, per z JF, Moor man AC, Holmberg SD. Non hospital health care. Associated hepatitis B and C virus transmission: United States 1998 -2008. Ann intern Med 2009. 150: 33.
13. Gerberdingj L. The infection health care provider. NEngijmed 1996 : 334 : 594
14. Dickson Rc, Everhart JE, lake JR, et al Transmission of hepatitis B by Transplantation of liver from donors positive for antibody to hepatitis B core antigen. Gastroenterology 1997 : 113: 1668
15. Wright l, Mamish D, combs c, et al. HEPATITIS B virus and apparent fulminant non .A, non – Bhepatitis . lancet 192 : 339: 952
16. Beasley RP, H wang LY, lincc,etal . Incidence & hepatitis Bvirus infection in preschool children in Taiwan. j infection D: S 1982 : 146 : 18.
17. Coursaget p, y vonnet B, chotard j , eta l . Age. and sex –related study of hepatitis B virus chronic carrier state in infants from endemic area ( Senegal) . j Med virol 1987 :22 :1.
18. Haber BA, Block J m, Jonas MM, et al Recommendations for screening, monitoring and referral of pediatric chronic hepatitis B pediatrics 2009; 124: e 1007
19. Krugmans, over by LR Mushahwarik, et al. Viral hepatitis type B studies on Natural history and prevention re-examined .N Engl J Med, 2000; 300:101.
20. Shepard CW, Finelli L, Alter MJ. Global epidemiology of Hepatitis C virus infection. Lancet Infect. Dis. 2005; 5: 558- 67.
21. 22. Badur S, Akgun A. Diagnosis of hepatitis B infections and monitoring of treatment. J Clin Virol 2001; 21: 229-237
22. 23. Allain JP. Occult hepatitis B virus infection. Transfus Clin Biol 2004; 11: 18-25
23. 24. Park K. Textbook of, preventive and social medicine. 20th ed. Jabalpur, India: Bhanot; 2009. 184- 94.
24. 25. Lt Col PK Gupta , Col H Kumar , Mr DR Basannar , Brig M Jaiprakash . Transfusion Transmitted Infections in Armed Forces : Prevalence and Trends :MJAFI ; 2006 ; 62 : 348– 350.
25. 26. Okoroiwu, H. U., Okafor, I. M., Asemota, E. A., Okpokam, D. C. (2018): Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation, BMC Public Health, vol 18(1), PP:645
Downloads
Published
2019-01-28
Issue
Section
Research Articles
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- Author must Submit Copyright form After acceptance of Article
How to Cite
1.
Osman RA, Ali MA. Prevalence of Hepatitis B Virus Among Patients Receiving Multiple Blood Transfusions in Khartoum: Multiple Blood Transfusions. Int J of Pharmc Res [Internet]. 2019 Jan. 28 [cited 2024 Oct. 18];9(1):e5020. Available from: https://ssjournals.co.in/index.php/ijpr/article/view/5020