Prescribing pattern of antihypertensive in hypertensive patients with compelling indication

Abstract

Aim: The aim of the study is to assess the various prescribing patterns in hypertension and compiling indications with JNC 8 guidelines. Objective : To assess the prescribing pattern in hypertensive patients and to evaluate the rationality in regards to JNC-8 Guidelines in a tertiary care hospital. Methods : It was a prospective, observational study conducted for 3 months in 250 hypertensive prescriptions with comorbidities who get admitted in the hospital were screened for the study. The data collected from the participants was entered into Microsoft excel spreadsheet. Results : A total of 250 hypertensive patients with different comorbidities were included in which 140 males and 110 females. The most commonly reported first three co-morbidities along with hypertension were diabetes mellitus 139 (55.6%), and coronary artery disease 48 (19.2%). Monotherapy was given in almost 166 (66.4%) patients and dual drug therapy was indicated in 52 (20.8%) patients, triple therapy was used only in 7 (2.8%) patients in the total sample size. Quadruple therapy is not preferred combination therapy which accounts only in 25(10%) patients. Conclusion: We conclude that calcium channel blockers and angiotensin II receptor blockers were the most frequently prescribed class of drugs; moreover single or in combination with other class of drugs for effective control of blood pressure patients with different compelling indications. Monotherapy was preferred than combination therapy.